ASTAGRAF XL 5 mg/1 (Tacrolimus Extended-Release Capsules CAPSULE, COATED, EXTENDED RELEASE) 5 mg/1

ASTAGRAF XL 5 mg/1 is a tacrolimus extended-release capsule used for immunosuppression. This medication helps prevent organ rejection after transplants. Learn more about its uses and effects.

Strength

5 mg/1

Pack Size

1 BOTTLE in 1 CARTON (0469-0687-73) / 30 CAPSULE, COATED, EXTENDED RELEASE in 1 BOTTLE

Manufacturer / TM Owner

Astellas Pharma US, Inc.

Select Quantity

Pack/s

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Indications & Clinical Uses

ASTAGRAF XL 5 mg/1 is primarily used to prevent organ rejection in transplant patients. Tacrolimus extended-release capsules work by suppressing the immune system, helping the body accept the transplanted organ. This medication is often prescribed for kidney, liver, or heart transplants. What is ASTAGRAF XL used for? It is used to manage immune system responses in transplant recipients.

Side Effects

Common effects of ASTAGRAF XL 5 mg/1 may include headaches, tremors, or high blood pressure. Some users might experience nausea, insomnia, or changes in kidney function. These effects can vary depending on individual health conditions and other medications being taken. Always consult a healthcare provider for personalized advice.

Precautions & Warnings

ASTAGRAF XL 5 mg/1 should be handled with care. Store the medication in a cool, dry place away from direct sunlight. Do not crush or chew the extended-release capsules. Follow the prescribed dosage and administration instructions provided by your healthcare provider. Avoid grapefruit and grapefruit juice, as they can interact with tacrolimus.

Avoid Interactions

ASTAGRAF XL 5 mg/1 may interact with certain medications, including CYP3A inhibitors and inducers. Alcohol and other immunosuppressants can also affect its efficacy. Always inform your healthcare provider about all medications you are taking to avoid potential interactions. Be cautious with over-the-counter drugs and herbal supplements.

Frequently Asked Questions

ASTAGRAF XL is used to prevent organ rejection in transplant patients by suppressing the immune system.

ASTAGRAF XL should be taken orally, usually once daily, with or without food. Follow your healthcare provider's instructions for the best results.

Common side effects may include headaches, tremors, high blood pressure, nausea, insomnia, and changes in kidney function.

It is generally advised to avoid alcohol while taking ASTAGRAF XL, as it may interact with the medication and cause adverse effects.

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated: 29 Jul 2026

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