Bupivacaine Hydrochloride and Epinephrine 2.5 mg/mL (Bupivacaine Hydrochloride and Epinephrine INJECTION, SOLUTION) 2.5 mg/mL

Bupivacaine Hydrochloride and Epinephrine 2.5 mg/mL is a local anesthetic solution used for infiltration and perineural administration. It combines bupivacaine, known for its long-lasting numbing effects, with epinephrine to enhance effectiveness and reduce bleeding. This injection is commonly used in medical procedures requiring localized pain relief.

Strength

2.5 mg/mL

Pack Size

25 CARTON in 1 BOX (0409-9043-01) / 1 VIAL, MULTI-DOSE in 1 CARTON (0409-9043-11) / 50 mL in 1 VIA

Manufacturer / TM Owner

Hospira, Inc.

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Indications & Clinical Uses

Bupivacaine Hydrochloride and Epinephrine 2.5 mg/mL is primarily used for local anesthesia, providing pain relief during medical procedures. It is often administered for infiltration or perineural blocks, where its long-acting formula helps manage pain effectively. This combination is also used to minimize bleeding at the injection site due to the vasoconstrictive properties of epinephrine.

Side Effects

When administered, Bupivacaine Hydrochloride and Epinephrine 2.5 mg/mL typically numbs the targeted area, reducing pain sensations. The addition of epinephrine can prolong the anesthetic effect and reduce bleeding by constricting blood vessels. Users may experience temporary numbness or tingling at the injection site.

Precautions & Warnings

This solution should be handled with care, ensuring proper sterile techniques are followed during administration. It is important to follow medical guidelines regarding dosage and administration to avoid potential complications. Always consult a healthcare provider before use, especially if there are known allergies or sensitivities to local anesthetics.

Avoid Interactions

Bupivacaine Hydrochloride and Epinephrine 2.5 mg/mL may interact with other medications, particularly those affecting blood pressure or heart rate. It is advisable to inform healthcare providers about all current medications to avoid adverse interactions. Alcohol and certain other substances may also influence the effects of this anesthetic solution.

Frequently Asked Questions

It is used for local anesthesia, providing pain relief during medical procedures through infiltration or perineural administration.

Epinephrine constricts blood vessels, which can prolong the anesthetic effect and reduce bleeding at the injection site.

Common effects include numbness and tingling at the injection site, along with prolonged pain relief due to the combined action of bupivacaine and epinephrine.

Yes, it is important to follow sterile techniques and medical guidelines for administration to avoid complications. Consult a healthcare provider if there are known allergies or sensitivities.

Yes, it may interact with medications affecting blood pressure or heart rate. Always inform healthcare providers about all current medications.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated: 29 Jul 2026

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