Product image of Cevimeline Hydrochloride 30 mg/1 (Cevimeline Hydrochloride) 30 mg/1 CAPSULE supplied by GNH India

Cevimeline Hydrochloride 30 mg/1

Active Ingredient:
Cevimeline Hydrochloride
Form:
CAPSULE
Brand:
Cevimeline Hydrochloride
Origin:
USA

Cevimeline Hydrochloride 30 mg/1 (Cevimeline Hydrochloride CAPSULE) 30 mg/1

Cevimeline Hydrochloride, the active ingredient in Cevimeline Hydrochloride 30 mg, is a muscarinic receptor agonist presented as a 30 mg capsule for oral use. It is used to treat symptoms of dry mouth in patients with Sjögren's syndrome, a condition that affects the immune system and causes dryness in certain parts of the body such as the eyes and mouth.

GNH India supplies Cevimeline Hydrochloride 30 mg as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide.

Strength

30 mg/1

Pack Size

100 CAPSULE in 1 BOTTLE (33342-216-11)

Manufacturer / TM Owner

Macleods Pharmaceuticals Limited

1
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Indications & Clinical Uses

Cevimeline Hydrochloride is a muscarinic receptor agonist used to treat symptoms of dry mouth associated with Sjögren's syndrome and other conditions that reduce saliva production.

  • Sjögren's syndrome: Increases saliva production to alleviate dry mouth symptoms.
  • Radiation-induced xerostomia: Helps manage dry mouth caused by radiation therapy.
  • Other autoimmune conditions: May be used to treat dry mouth in conditions similar to Sjögren's syndrome.

How It Works

  • Cevimeline Hydrochloride works by stimulating muscarinic (M3) receptors in the salivary glands. This stimulation increases the production of saliva, helping to relieve dry mouth symptoms in patients with Sjögren's syndrome and other related conditions. The drug mimics the action of acetylcholine, a natural neurotransmitter, to enhance glandular function and improve moisture levels in the mouth.

Side Effects

Cevimeline Hydrochloride may cause various side effects, ranging from common to serious. Common Side Effects:

  • Excessive sweating
  • Nausea
  • Runny nose (rhinitis)
  • Diarrhea
  • Headache
  • Dizziness
  • Blurred vision

Serious or Rare Side Effects

  • Severe nausea or vomiting
  • Indigestion or stomach pain
  • Itchy skin
  • Light-colored stools
  • Yellow eyes or skin
  • Bloody or cloudy urine
  • Pain in the lower back or side
  • Chest pain or tightness
  • Irregular heartbeat
  • Swelling of the face, fingers, feet, or lower legs

Precautions & Warnings

Cevimeline Hydrochloride should be used with caution in certain patient populations and conditions. Always follow your healthcare provider's advice and the prescribed dosage.

  • Asthma, uncontrolled: Contraindicated in patients with uncontrolled asthma.
  • Hypersensitivity: Not recommended for patients with known hypersensitivity to cevimeline.
  • Acute iritis: Avoid use in patients with acute iritis or narrow-angle glaucoma.
  • Cardiovascular disease: Use with caution in patients with a history of cardiovascular disease.
  • Pulmonary disease: Administer with caution in patients with controlled asthma, chronic bronchitis, or chronic obstructive pulmonary disease (COPD).
  • Ocular effects: May cause visual blurring, especially at night or in reduced lighting.
  • Store at room temperature: Keep in the original container, tightly closed, and away from moisture and light.

Avoid Interactions

Cevimeline Hydrochloride may interact with other medications, potentially altering its effectiveness or increasing the risk of side effects. Major Interactions (Avoid):

  • Beta-blockers: May exacerbate cardiovascular effects.
  • Anticholinergic drugs: May reduce the effectiveness of cevimeline.
  • Drugs that increase bronchial secretions: May worsen respiratory conditions.

Moderate Interactions (Monitor Closely)

  • Cardiovascular medications: May alter heart rate or rhythm.
  • Ophthalmic medications: May cause visual disturbances.
  • Drugs affecting gastrointestinal motility: May increase the risk of gastrointestinal side effects.

Frequently Asked Questions

Cevimeline Hydrochloride is used to treat symptoms of dry mouth in patients with Sjögren's syndrome, a condition that affects the immune system and causes dryness in certain parts of the body. It is also used to manage dry mouth caused by radiation therapy and other autoimmune conditions.

Cevimeline Hydrochloride works by stimulating muscarinic (M3) receptors in the salivary glands. This stimulation increases the production of saliva, helping to relieve dry mouth symptoms. The drug mimics the action of acetylcholine, a natural neurotransmitter, to enhance glandular function and improve moisture levels in the mouth.

The usual dose of Cevimeline Hydrochloride is 30 mg taken three times a day. However, the exact dosage should be determined by your healthcare provider based on your specific condition and medical history. Always follow your doctor's instructions for the best results.

The safety of Cevimeline Hydrochloride during pregnancy or breastfeeding has not been established. It is important to consult with your healthcare provider to discuss the potential risks and benefits before using this medication if you are pregnant or breastfeeding.

To order Cevimeline Hydrochloride from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets and will ask the buyer to confirm trade or institutional credentials. The team will then reply with pricing, availability, shipping, and the import paperwork.

Cevimeline Hydrochloride is a muscarinic receptor agonist specifically designed to increase saliva production in patients with Sjögren's syndrome. Compared to other treatments like artificial saliva substitutes or pilocarpine, cevimeline has a more targeted mechanism of action and may be more effective in certain patients. However, the choice of treatment depends on individual patient needs and should be discussed with a healthcare provider.

Cevimeline Hydrochloride should be stored at room temperature, away from moisture and light. Keep the medication in its original container, tightly closed, and out of reach of children. Avoid exposing the capsules to excessive heat or humidity, as this may affect their stability and effectiveness.

Cevimeline Hydrochloride is administered orally in capsule form. The capsules should be taken with or without food, as directed by your healthcare provider. It is important to take the medication at the same times each day to maintain consistent levels of the drug in your body.

The most serious risks associated with Cevimeline Hydrochloride include severe nausea or vomiting, indigestion or stomach pain, itchy skin, light-colored stools, yellow eyes or skin, bloody or cloudy urine, pain in the lower back or side, chest pain or tightness, and irregular heartbeat. If you experience any of these symptoms, seek medical attention immediately.

Cevimeline Hydrochloride should not be used by patients with uncontrolled asthma, known hypersensitivity to cevimeline, acute iritis, or narrow-angle glaucoma. It should also be used with caution in patients with a history of cardiovascular disease, chronic bronchitis, or chronic obstructive pulmonary disease (COPD). Always consult with your healthcare provider to determine if this medication is suitable for you.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

References

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