Product image of CHANTIX 1 mg/1 (Varenicline Tartrate) 1 mg/1 TABLET, FILM COATED supplied by GNH India

CHANTIX 1 mg/1

Active Ingredient:
Varenicline Tartrate
Form:
TABLET, FILM COATED
Brand:
CHANTIX
Origin:
USA

CHANTIX 1 mg/1 (Varenicline Tartrate TABLET, FILM COATED) 1 mg/1

Varenicline, the active ingredient in CHANTIX, is a partial agonist of α4β2 nicotinic acetylcholine receptors presented as a 1 mg film-coated tablet for oral use. It is indicated for smoking cessation in adults.

GNH India supplies CHANTIX as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide.

Strength

1 mg/1

Pack Size

56 TABLET, FILM COATED in 1 BOTTLE (0069-0469-56)

Manufacturer / TM Owner

Pfizer Laboratories Div Pfizer Inc

1
Pack/s
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Indications & Clinical Uses

CHANTIX is a smoking cessation aid that helps reduce nicotine cravings and withdrawal symptoms.

  • Smoking cessation: Helps adults quit smoking by reducing cravings and withdrawal symptoms.
  • Smoking reduction: For patients who are not ready to quit abruptly, it can help gradually reduce smoking habits over time.
  • Long-term abstinence: Recommended for an additional 12 weeks after initial treatment to increase the likelihood of sustained smoking cessation.

How It Works

  • CHANTIX works by binding to α4β2 nicotinic acetylcholine receptors in the brain, acting as a partial agonist. This reduces the cravings and withdrawal symptoms associated with quitting smoking by mimicking the effects of nicotine but without the addictive properties. It also blocks nicotine from binding to these receptors, further reducing the reward and reinforcement associated with smoking.

Side Effects

CHANTIX can cause various side effects, ranging from mild to severe.

Common Side Effects

  • Nausea: Often mild or moderate and may be transient.
  • Headache: Common but usually manageable.
  • Vomiting: Can occur, especially during the initial stages of treatment.
  • Insomnia: Difficulty sleeping may be experienced.
  • Abnormal dreams: Vivid or unusual dreams are reported.
  • Dizziness: Some patients may experience lightheadedness.
  • Constipation: Can occur as a side effect.
  • Dry mouth: A common but usually mild side effect.

Serious or Rare Side Effects

  • Mood changes: Including depression, anxiety, and agitation.
  • Suicidal thoughts: Rare but serious, requiring immediate medical attention.
  • Seizures: Rare but possible, especially in patients with a history of seizures.
  • Allergic reactions: Such as rash, itching, or swelling, which require immediate medical attention.

Precautions & Warnings

CHANTIX should be used with caution and under medical supervision.

  • Prescription use: Only use CHANTIX as prescribed by a healthcare provider.
  • Mental health monitoring: Regularly monitor for changes in mood or behavior.
  • Seizure history: Use with caution in patients with a history of seizures.
  • Renal impairment: Adjust dosage for patients with severe renal impairment.
  • Pregnancy: Consult a healthcare provider before use during pregnancy.
  • Breastfeeding: Consult a healthcare provider before use while breastfeeding.
  • Store below 25°C: Keep in the original pack, protect from moisture.

Avoid Interactions

CHANTIX can interact with other medications, potentially affecting its efficacy or increasing the risk of side effects.

Major Interactions (Avoid)

  • Nicotine replacement therapy: Avoid concurrent use to prevent adverse effects.
  • Bupropion: Avoid concurrent use due to increased risk of seizures.
  • Insulin: Monitor blood glucose levels closely when starting or stopping CHANTIX.

Moderate Interactions (Monitor Closely)

  • Antidepressants: Monitor for increased risk of mood changes.
  • Antipsychotics: Monitor for increased risk of side effects.
  • Alcohol: Monitor for increased risk of side effects such as dizziness and drowsiness.

Frequently Asked Questions

CHANTIX is used as an aid to smoking cessation. It helps reduce nicotine cravings and withdrawal symptoms, making it easier for adults to quit smoking. It can also be used to gradually reduce smoking habits over time for those not ready to quit abruptly.

Varenicline, the active ingredient in CHANTIX, works by binding to α4β2 nicotinic acetylcholine receptors in the brain. It acts as a partial agonist, reducing the cravings and withdrawal symptoms associated with quitting smoking by mimicking the effects of nicotine without the addictive properties. It also blocks nicotine from binding to these receptors, further reducing the reward and reinforcement associated with smoking.

The usual dose of CHANTIX is determined by a healthcare provider. It typically starts with a lower dose and gradually increases to the recommended dose of 1 mg twice daily. The treatment duration is usually 12 weeks, with an additional 12 weeks recommended for those who have successfully stopped smoking to increase the likelihood of long-term abstinence.

The safety of CHANTIX during pregnancy or breastfeeding has not been fully established. It is important to consult a healthcare provider before using CHANTIX if you are pregnant or breastfeeding. They can provide guidance based on your specific situation and the potential benefits and risks.

To order CHANTIX from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets. The team will ask you to confirm your trade or institutional credentials and will reply with pricing, availability, shipping, and the necessary import paperwork.

CHANTIX is a partial agonist of α4β2 nicotinic acetylcholine receptors, which helps reduce nicotine cravings and withdrawal symptoms. Compared to other smoking cessation aids like nicotine replacement therapy (NRT) or bupropion, CHANTIX has been shown to be effective in helping smokers quit. However, the choice of treatment depends on individual preferences, medical history, and the advice of a healthcare provider.

CHANTIX should be stored below 25°C, kept in the original pack, and protected from moisture. It is important to follow the storage instructions provided with the medication to ensure its effectiveness and safety. Always keep medications out of reach of children and pets.

CHANTIX is taken orally, with or without food, and should be swallowed whole with a full glass of water. It is important to follow the dosing schedule prescribed by your healthcare provider. The tablets should not be crushed, chewed, or broken.

The most serious risks associated with CHANTIX include mood changes, such as depression, anxiety, and agitation, as well as suicidal thoughts. Rare but serious side effects can include seizures, especially in patients with a history of seizures, and allergic reactions. It is important to monitor for these symptoms and seek immediate medical attention if they occur.

CHANTIX should not be used by individuals who are allergic to varenicline or any of the inactive ingredients in the medication. It should also be used with caution in patients with a history of seizures, mental health conditions, or severe renal impairment. Always consult a healthcare provider before starting CHANTIX to ensure it is safe for you.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

References

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