Collagenase Santyl (Collagenase Clostridium Histolyticum Ointment) 250 units/g x30g

Collagenase Santyl (Collagenase Clostridium Histolyticum) ointment 250 units/g is a prescription topical enzyme therapy. It helps remove dead tissue from wounds, supporting natural healing. Commonly used for chronic wounds and burns. Prescription required for safe use.

Strength

250 units/g x30g

Manufacturer / TM Owner

SMITH & NEPHEW, INC

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Indications & Clinical Uses

Collagenase Santyl ointment is primarily used to help remove dead or damaged tissue from wounds, including chronic ulcers and burns. It works by breaking down collagen in non-viable tissue, allowing healthy tissue to regenerate. This enzyme-based therapy is often prescribed when wounds are slow to heal or have necrotic tissue present. It is not intended for use on healthy skin.

Side Effects

When applied as directed, Collagenase Santyl ointment helps gently dissolve dead tissue without harming surrounding healthy skin. Users may notice a gradual reduction in wound debris over time. The ointment is designed to be applied once daily and may be covered with a sterile dressing. Most effects are observed as part of the wound healing process rather than immediate symptom relief.

Precautions & Warnings

Collagenase Santyl should only be used as prescribed by a healthcare provider. Avoid contact with eyes, mouth, or healthy skin, as it is intended for wound application only. Keep the tube tightly closed when not in use and store at room temperature. Do not use if the ointment changes color or shows signs of contamination. Always wash hands before and after application.

Avoid Interactions

No significant drug interactions have been widely reported with Collagenase Santyl ointment. However, it is important to inform your healthcare provider about all medications and supplements you are using. Avoid using other topical treatments on the same wound unless directed by a doctor. Keep the wound clean and follow wound care instructions to prevent infection.

Frequently Asked Questions

Collagenase Santyl is used to help remove dead tissue from wounds, supporting the healing of chronic ulcers and burns.

It is typically applied once daily or as directed by a healthcare provider. Always follow the prescribed application schedule.

No, it is formulated for use on wounds with dead tissue only. Avoid applying it to healthy skin.

Yes, Collagenase Santyl is a prescription medication and should only be used under medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated: 28 Jul 2026

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