Estradiol .0375 mg/d (Estradiol PATCH) .0375 mg/d

Estradiol .0375 mg/d is a transdermal patch designed to deliver estradiol, a form of estrogen, through the skin. It is commonly used for hormone replacement therapy in women experiencing menopause. This patch provides a steady release of estradiol over several days, helping to manage symptoms associated with low estrogen levels.

Strength

.0375 mg/d

Pack Size

8 POUCH in 1 CARTON (0378-4643-26) / 1 PATCH in 1 POUCH (0378-4643-16) / 3.5 d in 1 PATCH

Manufacturer / TM Owner

Mylan Pharmaceuticals Inc.

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Pack/s

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Indications & Clinical Uses

Estradiol .0375 mg/d is primarily used for hormone replacement therapy in women who are experiencing symptoms of menopause, such as hot flashes, night sweats, and vaginal dryness. It can also be used to prevent osteoporosis in postmenopausal women. The patch delivers estradiol transdermally, which may help to reduce the risk of certain side effects associated with oral estrogen therapy. What is estradiol used for? It is used to replenish estrogen levels in the body, which can decline due to menopause or other conditions.

Side Effects

Common effects of using estradiol .0375 mg/d may include relief from menopausal symptoms such as hot flashes and vaginal dryness. Some users may also experience improvements in mood and sleep quality. However, individual responses can vary, and it is important to monitor for any adverse reactions. Side effects may include skin irritation at the application site, breast tenderness, and nausea.

Precautions & Warnings

Estradiol .0375 mg/d should be used with caution, especially in individuals with a history of blood clots, liver disease, or certain types of cancer. It is important to follow the instructions provided by a healthcare professional regarding the application and removal of the patch. The patch should be applied to clean, dry skin and changed according to the prescribed schedule. Avoid exposing the patch to direct sunlight or heat sources.

Avoid Interactions

Estradiol .0375 mg/d may interact with certain medications, including blood thinners, anticonvulsants, and some antibiotics. It is important to inform a healthcare professional about all medications being taken to avoid potential interactions. Alcohol consumption should also be moderated, as it may affect the effectiveness of the patch. Always consult a healthcare professional before starting or stopping any medication.

Frequently Asked Questions

Estradiol .0375 mg/d is used for hormone replacement therapy in women experiencing menopausal symptoms or to prevent osteoporosis in postmenopausal women.

The patch should be applied to clean, dry skin, typically on the lower abdomen, buttocks, or upper body. Follow the instructions provided by your healthcare professional for specific application and removal guidelines.

Common side effects may include skin irritation at the application site, breast tenderness, and nausea. Individual responses can vary, so it is important to monitor for any adverse reactions.

Estradiol .0375 mg/d should be used with caution in individuals with a history of blood clots. Consult a healthcare professional for personalized advice.

The patch is typically changed every 3 to 4 days, but follow the specific instructions provided by your healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated: 29 Jul 2026

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