Estradiol Transdermal System .0375 mg/d (Estradiol PATCH) .0375 mg/d

Estradiol Transdermal System .0375 mg/d is a hormone replacement therapy patch designed to deliver estradiol through the skin. It is commonly used to manage symptoms of menopause, such as hot flashes and vaginal dryness. This transdermal system provides a consistent dose of estradiol over a week.

Strength

.0375 mg/d

Pack Size

4 PATCH in 1 CARTON (0781-7122-54) / 7 d in 1 PATCH (0781-7122-58)

Manufacturer / TM Owner

Sandoz Inc

Select Quantity

Pack/s

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Indications & Clinical Uses

Estradiol Transdermal System .0375 mg/d is primarily used for hormone replacement therapy in women experiencing menopausal symptoms. These symptoms can include hot flashes, night sweats, and vaginal dryness. The patch delivers estradiol, a form of estrogen, through the skin to help alleviate these discomforts. It is often prescribed to women who cannot or prefer not to take oral hormone replacement therapies.

Side Effects

Common effects of using the Estradiol Transdermal System .0375 mg/d may include skin irritation at the application site. Some users may experience breast tenderness, headaches, or fluid retention. These effects vary among individuals and are not experienced by everyone. It is important to monitor for any adverse reactions and consult a healthcare provider if concerns arise.

Precautions & Warnings

When using the Estradiol Transdermal System .0375 mg/d, it is important to follow the instructions for application and removal carefully. The patch should be applied to clean, dry skin and changed as directed. Avoid exposing the patch to excessive heat or sunlight. Individuals with a history of blood clots, liver disease, or certain cancers should discuss the use of this patch with their healthcare provider.

Avoid Interactions

The Estradiol Transdermal System .0375 mg/d may interact with other medications, including those that affect liver enzymes. It is important to inform your healthcare provider about all medications you are taking, including over-the-counter drugs and supplements. Alcohol and certain foods may also affect the effectiveness of the patch. Always consult a healthcare provider for personalized advice.

Frequently Asked Questions

Estradiol Transdermal System .0375 mg/d is used for hormone replacement therapy to manage menopausal symptoms like hot flashes and vaginal dryness.

The patch should be changed as directed by your healthcare provider, typically once a week.

The patch is designed to stay in place during daily activities, including swimming and showering, but it should be checked regularly for adhesion.

If you experience skin irritation, consult your healthcare provider for advice on managing the irritation or adjusting the treatment.

The patch may not be suitable for individuals with certain medical conditions, such as a history of blood clots or specific cancers. Always consult a healthcare provider.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated: 29 Jul 2026

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