Product image of Estradot 25 25 mcg (Estradiol) 25 MCG PATCH supplied by GNH India

Estradot 25 25 mcg

Active Ingredient:
Estradiol
Form:
PATCH
Brand:
ESTRADOT 25
Origin:
CANADA

Estradot 25 25 mcg (Estradiol PATCH) 25 MCG

Estradiol, the active ingredient in Estradot 25, is an estrogen receptor agonist presented as a 25 mcg transdermal patch for transdermal use. It is used for the management of menopausal symptoms and the prevention of osteoporosis in postmenopausal women.

GNH India supplies Estradot 25 as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide.

Strength

25 MCG

Pack Size

8

Manufacturer / TM Owner

SANDOZ CANADA INCORPORATED

1
Pack/s
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Indications & Clinical Uses

Estradot 25 is a hormone replacement therapy (HRT) used to manage symptoms associated with menopause and to prevent osteoporosis in postmenopausal women.

  • Moderate to severe vasomotor symptoms: Relief of hot flushes, sweating, and chills associated with menopause.
  • Osteoporosis prevention: Helps prevent bone loss and fractures in postmenopausal women at risk of osteoporosis.
  • Hypoestrogenism: Treatment of symptoms due to ovarian failure or hypogonadism.

How It Works

  • Estradot 25 works by binding to estrogen receptors (ERα and ERβ) and modulating the transcription of estrogen-responsive genes. This restores estrogenic activity in target tissues, alleviating symptoms of menopause and preventing osteoporosis.

Side Effects

Estradot 25 may cause side effects, although not everyone experiences them. Common Side Effects:

  • Skin irritation at the application site.
  • Breast tenderness or swelling.
  • Headache.
  • Abdominal bloating or cramps.
  • Nausea.
  • Vaginal bleeding or spotting.

Serious or Rare Side Effects

  • Increased risk of blood clots.
  • Stroke or heart attack.
  • Gallbladder disease.
  • Liver problems.
  • Increased risk of endometrial cancer in women with a uterus.

Precautions & Warnings

Estradot 25 should be used with caution and under medical supervision. Consult your healthcare provider before use if you have any of the following conditions:

  • History of blood clots or stroke.
  • Liver disease.
  • Breast cancer or a history of breast cancer.
  • Unexplained vaginal bleeding.
  • Heart disease or high blood pressure.
  • Store below 25°C: Keep in the original pack, protect from moisture.

Avoid Interactions

Estradot 25 may interact with other medications, so it is important to inform your healthcare provider about all the medications you are taking. Major Interactions (Avoid):

  • Anticoagulants: Increased risk of bleeding.
  • Tamoxifen: May reduce the effectiveness of tamoxifen.
  • Moderate Interactions (Monitor Closely):
  • Anticonvulsants: May reduce the effectiveness of Estradot 25.
  • Rifampin: May reduce the effectiveness of Estradot 25.
  • St. John's Wort: May reduce the effectiveness of Estradot 25.

Frequently Asked Questions

Estradot 25 is used to manage moderate to severe vasomotor symptoms associated with menopause, such as hot flushes, sweating, and chills. It is also used to prevent osteoporosis in postmenopausal women at risk of bone loss and fractures.

Estradot 25 contains estradiol, which binds to estrogen receptors (ERα and ERβ) and modulates the transcription of estrogen-responsive genes. This restores estrogenic activity in target tissues, alleviating menopausal symptoms and preventing osteoporosis.

The dosage of Estradot 25 is determined by your healthcare provider based on your medical condition, response to treatment, and other factors. Always follow your prescriber's instructions for use.

Estradot 25 is not recommended for use during pregnancy or while breastfeeding. If you become pregnant, stop using Estradot 25 and contact your doctor immediately.

To order Estradot 25 from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets and will ask you to confirm your trade or institutional credentials. The team will then provide pricing, availability, shipping, and import paperwork details.

Estradot 25 is a transdermal patch that delivers estradiol through the skin. It is designed to provide a steady release of the hormone, which can help minimize side effects compared to oral estrogen therapies. The choice between different HRT options depends on individual health profiles and preferences.

Estradot 25 should be stored below 25°C, kept in the original pack, and protected from moisture. Always follow the storage instructions provided with the medication to ensure its effectiveness and safety.

Estradot 25 is applied as a transdermal patch to the skin. The patch should be replaced twice weekly (every 3 to 4 days) and applied to a different site each time to avoid skin irritation. Follow your healthcare provider's instructions for proper application and replacement.

The most serious risks associated with Estradot 25 include an increased risk of blood clots, stroke, heart attack, gallbladder disease, liver problems, and endometrial cancer in women with a uterus. Report any unusual symptoms to your healthcare provider immediately.

Estradot 25 should not be used by individuals with a history of breast cancer, blood clots, liver disease, unexplained vaginal bleeding, or those who are pregnant or breastfeeding. Always consult your healthcare provider before starting Estradot 25.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

References

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