Product image of Eylea 2 mg (Aflibercept) 2 MG SOLUTION supplied by GNH India

Eylea 2 mg

Active Ingredient:
Aflibercept
Form:
SOLUTION
Brand:
EYLEA
Origin:
CANADA

Eylea 2 mg (Aflibercept SOLUTION) 2 MG

Aflibercept, the active ingredient in Eylea 2 mg, is a VEGF inhibitor presented as a 2 mg solution for intravitreal use. It is used to treat various eye conditions involving abnormal blood vessel growth in adults and premature infants. GNH India supplies Eylea 2 mg as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals and clinics worldwide.

Eylea 2 mg is specifically designed to address conditions that affect the retina, a critical part of the eye responsible for vision. This medication is administered directly into the vitreous humor of the eye to target and inhibit the growth of abnormal blood vessels.

Strength

2 MG

Pack Size

278 MICROLITERS

Manufacturer / TM Owner

BAYER INC

1
Pack/s
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Indications & Clinical Uses

Eylea 2 mg is used to treat conditions related to abnormal blood vessel growth in the retina. It is indicated for the following:

  • Neovascular age-related macular degeneration: Reduces the growth of abnormal blood vessels in the retina, preventing vision loss.
  • Macular edema secondary to retinal vein occlusion: Decreases swelling in the macula caused by blocked veins in the retina.
  • Diabetic macular edema: Helps to reduce swelling in the macula due to diabetic retinopathy.
  • Myopic choroidal neovascularization: Treats abnormal blood vessel growth in the choroid, a layer of the eye, due to severe myopia.

How It Works

  • Eylea 2 mg works by binding to vascular endothelial growth factor (VEGF)-A, VEGF-B, and placental growth factor (PlGF). By binding to these factors, Eylea prevents the activation of VEGF receptors, thereby inhibiting the growth of new blood vessels. This mechanism helps to reduce abnormal blood vessel growth and leakage in the retina, which is crucial in treating various eye conditions.

Side Effects

Eylea 2 mg, like all medications, can cause side effects. Common Side Effects:

  • Eye pain or redness at the injection site.
  • Increased floaters in the vision.
  • Conjunctival hemorrhage (small bleeding spots in the eye).
  • Cataracts or increased intraocular pressure.

Serious or Rare Side Effects

  • Endophthalmitis (severe eye infection).
  • Retinal detachment (separation of the retina from the back of the eye).
  • Increased risk of arterial thromboembolic events (e.g., heart attack or stroke).
  • Severe vision loss or blindness.

Precautions & Warnings

Eylea 2 mg should be used with caution and under the supervision of a healthcare professional. Important precautions include:

  • Informed consent: Ensure the patient understands the risks and benefits of the treatment.
  • Monitoring: Regular eye examinations are necessary to monitor for side effects and treatment efficacy.
  • Infection risk: The injection site must be kept clean to prevent infection.
  • Pre-existing conditions: Patients with a history of eye infections or inflammation should be closely monitored.
  • Pregnancy and breastfeeding: The safety of Eylea 2 mg during pregnancy and breastfeeding is not established.
  • Storage: Store at 2-8°C: Keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Eylea 2 mg may interact with other medications, requiring careful management. Major Interactions (Avoid):

  • Other intravitreal agents: Avoid concurrent use with other intravitreal medications to prevent adverse interactions.
  • Systemic anti-VEGF therapies: Avoid combining with systemic VEGF inhibitors to reduce the risk of systemic side effects.

Moderate Interactions (Monitor Closely)

  • Immunosuppressants: Monitor for increased risk of infections when used with immunosuppressant drugs.
  • Anticoagulants: Closely monitor for signs of bleeding or thromboembolic events.
  • Anti-inflammatory drugs: Monitor for increased risk of eye inflammation or infection.

Frequently Asked Questions

Eylea 2 mg is used to treat various eye conditions involving abnormal blood vessel growth in the retina. These conditions include neovascular age-related macular degeneration, macular edema secondary to retinal vein occlusion, diabetic macular edema, and myopic choroidal neovascularization. The medication helps to reduce the growth of abnormal blood vessels and prevent vision loss.

Aflibercept, the active ingredient in Eylea 2 mg, works by binding to vascular endothelial growth factor (VEGF)-A, VEGF-B, and placental growth factor (PlGF). By binding to these factors, Aflibercept prevents the activation of VEGF receptors, thereby inhibiting the growth of new blood vessels. This mechanism helps to reduce abnormal blood vessel growth and leakage in the retina, which is crucial in treating various eye conditions.

The dosage of Eylea 2 mg is determined by a healthcare professional based on the patient's condition and response to treatment. It is typically administered as an intravitreal injection, and the frequency of injections is adjusted according to the patient's needs. Always follow the prescribed dosage and administration instructions provided by your healthcare provider.

The safety of Eylea 2 mg during pregnancy and breastfeeding has not been established. It is important to discuss the potential risks and benefits with your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. Your healthcare provider can help you make an informed decision based on your specific situation.

To order Eylea 2 mg from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets. The team will ask you to confirm your trade or institutional credentials and will reply with pricing, availability, shipping (including cold-chain where relevant), and the import paperwork.

Eylea 2 mg is one of several treatments available for macular degeneration. It is a VEGF inhibitor that works by reducing the growth of abnormal blood vessels in the retina. Compared to other treatments, Eylea 2 mg has been shown to be effective in improving or maintaining vision in patients with neovascular age-related macular degeneration. Your healthcare provider can help you determine the best treatment option based on your specific condition and needs.

Eylea 2 mg should be stored at 2-8°C, kept refrigerated, and protected from light. It is important not to freeze or shake the medication. Always follow the storage and handling instructions provided by your healthcare provider or the product packaging to ensure the medication remains effective and safe to use.

Eylea 2 mg is administered as an intravitreal injection, which means it is injected directly into the vitreous humor of the eye. This procedure is typically performed by a healthcare professional in a clinical setting. The injection is usually well-tolerated, but some patients may experience mild discomfort or side effects such as eye pain or redness at the injection site.

While Eylea 2 mg is generally well-tolerated, there are some serious risks to be aware of. These include endophthalmitis (severe eye infection), retinal detachment, and increased risk of arterial thromboembolic events such as heart attack or stroke. It is important to monitor for any signs of these serious side effects and to seek immediate medical attention if they occur.

Eylea 2 mg should not be used by individuals who have a known hypersensitivity to Aflibercept or any of the excipients in the medication. It is also important to discuss your medical history with your healthcare provider, including any pre-existing eye conditions, infections, or other health issues, to determine if Eylea 2 mg is suitable for you. Always follow the advice of your healthcare provider regarding the use of this medication.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

References

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