Product image of Intercold (Chlorphenamine Maleate, Phenylephrine Bitartrate, Paracetamol) supplied by GNH India

Intercold

Active Ingredient:
Chlorphenamine Maleate, Phenylephrine Bitartrate, Paracetamol
Origin:
EU

Intercold (Chlorphenamine Maleate, Phenylephrine Bitartrate, Paracetamol)

Chlorphenamine maleate, phenylephrine bitartrate and paracetamol, the active ingredients in Intercold, are antihistamine, decongestant and analgesic agents presented as an oral tablet for systemic use. They relieve common cold symptoms such as nasal congestion, headache and fever in adults and children.

GNH India supplies Intercold as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies and clinics worldwide.

Manufacturer / TM Owner

Interpharma, S.A.

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Indications & Clinical Uses

Intercold combines antihistamine, decongestant and analgesic actions to address the common cold and flu symptom complex.

  • Common cold: eases nasal congestion, runny nose and sneezing.
  • Headache: reduces pain associated with cold or flu.
  • Fever: lowers elevated body temperature.
  • Nasal congestion: improves airflow by shrinking swollen nasal mucosa.

How It Works

  • Chlorphenamine maleate blocks H1 histamine receptors, reducing allergic symptoms. Phenylephrine bitartrate stimulates α‑adrenergic receptors, causing vasoconstriction of nasal blood vessels and decreasing congestion. Paracetamol inhibits central prostaglandin synthesis, providing analgesic and antipyretic effects. The combined actions target multiple pathways involved in cold and flu manifestations.

Side Effects

Intercold may cause several adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Drowsiness: feeling unusually sleepy.
  • Dry mouth: reduced salivation leading to throat discomfort.
  • Nausea: mild stomach upset.
  • Increased blood pressure: transient rise in systolic pressure.

Serious or Rare Side Effects

  • Anaphylaxis: severe allergic reaction with breathing difficulty.
  • Severe liver injury: rare but possible with excessive paracetamol exposure.
  • Hypertensive crisis: marked elevation of blood pressure, especially with phenylephrine overuse.

Precautions & Warnings

Before using Intercold, consider the following precautions.

  • Allergy assessment: avoid if you are hypersensitive to any component.
  • Blood pressure monitoring: phenylephrine may raise pressure; use cautiously in hypertensive patients.
  • Liver health: limit use in individuals with hepatic impairment.
  • Alcohol avoidance: alcohol can increase risk of liver toxicity.
  • Dosage adherence: do not exceed the recommended amount.
  • Store at room temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Intercold can interact with other medicines; awareness helps prevent adverse outcomes.

Major Interactions (Avoid)

  • MAO inhibitors: risk of hypertensive crisis with phenylephrine.
  • Other hepatotoxic drugs: combined liver stress with paracetamol.
  • Other antihistamines: may increase sedation.

Moderate Interactions (Monitor Closely)

  • Antihypertensives: phenylephrine may diminish their effect.
  • Alcohol: enhances liver toxicity risk.
  • CYP450 inhibitors: may raise paracetamol plasma levels.

Frequently Asked Questions

Intercold is an over‑the‑counter oral tablet that combines an antihistamine, a decongestant and an analgesic to relieve common cold and flu symptoms such as nasal congestion, headache, fever, and general discomfort.

Chlorphenamine blocks H1 histamine receptors to reduce allergic symptoms, phenylephrine stimulates α‑adrenergic receptors causing nasal blood‑vessel constriction and less congestion, and paracetamol inhibits central prostaglandin synthesis, providing pain relief and fever reduction. The three mechanisms act synergistically to address multiple cold‑related complaints.

The appropriate dose of Intercold is determined by the prescribing healthcare professional based on the patient’s age, weight, and clinical condition. Patients should follow the prescriber’s instructions and never exceed the recommended amount.

Safety of Intercold in pregnancy or while breastfeeding has not been definitively established. Women who are pregnant, planning pregnancy, or nursing should discuss potential risks and benefits with their healthcare provider before using this product.

To order Intercold, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Intercold offers a three‑component formulation—antihistamine, decongestant and analgesic—in a single tablet, which can simplify therapy compared with using separate products. Some alternatives contain only one or two of these agents, potentially requiring multiple doses to achieve comparable symptom control.

Intercold should be stored at room temperature, below 25 °C, in its original packaging to protect it from moisture and light. Keep the tablet container tightly closed and out of reach of children.

Intercold is taken orally with a glass of water. The tablet should be swallowed whole and not chewed or crushed, unless otherwise directed by a healthcare professional.

Serious risks include severe allergic reactions such as anaphylaxis, rare but potentially life‑threatening liver injury from paracetamol overdose, and hypertensive crises caused by phenylephrine, especially in patients taking monoamine‑oxidase inhibitors or other vasoconstrictors.

Intercold should be avoided by individuals with known hypersensitivity to any of its ingredients, those taking MAO inhibitors, patients with severe liver disease, uncontrolled hypertension, or anyone advised by a clinician to refrain from antihistamines, decongestants, or paracetamol.

Reviewed by

Dr. Shweta Ashok More

M.Pharm (Quality Assurance), Ph.D. (Medicinal Chemistry)

Content approved 11 Aug 2026

Last updated:

References

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