Product image of Intrarosa 6.5 mg (Prasterone) 6.5 MG OVULE supplied by GNH India

Intrarosa 6.5 mg

Active Ingredient:
Prasterone
Form:
OVULE
Brand:
INTRAROSA
Origin:
UNITED STATES

Intrarosa 6.5 mg (Prasterone OVULE) 6.5 MG

Prasterone, the active ingredient in Intrarosa 6.5 mg, is an androgen (steroid hormone) presented as a 6.5 mg vaginal ovule for vaginal use. It is used to treat painful sexual intercourse in postmenopausal women due to vulvar and vaginal atrophy.

GNH India supplies Intrarosa 6.5 mg as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide.

Strength

6.5 MG

Manufacturer / TM Owner

COSETTE PHARMACEUTICALS, INC.

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Indications & Clinical Uses

Intrarosa 6.5 mg is indicated for the treatment of dyspareunia (painful sexual intercourse) associated with vulvar and vaginal atrophy (VVA) in postmenopausal women.

  • Dyspareunia: Reduces moderate to severe pain during sexual intercourse due to vaginal changes related to menopause.
  • Vulvar and vaginal atrophy (VVA): Improves vaginal tissue and symptoms associated with menopause-related atrophy.

How It Works

  • Intrarosa 6.5 mg contains prasterone, a manmade form of dehydroepiandrosterone (DHEA). Once administered, prasterone is converted intracellularly into active sex hormones, including estrogen and testosterone, in the vaginal tissues. This process helps restore the vaginal epithelium, improving lubrication and elasticity, which alleviates symptoms of vulvar and vaginal atrophy.

Side Effects

The use of Intrarosa 6.5 mg may cause certain side effects. Common Side Effects:

  • Vaginal discharge: May occur during treatment.
  • Changes on Pap smear: Abnormal results may be observed.

Serious or Rare Side Effects

  • Allergic reactions: Symptoms such as rash, itching, swelling, severe dizziness, or trouble breathing may occur.
  • Vaginal bleeding: Unchecked vaginal bleeding should be evaluated by a healthcare provider.
  • Breast cancer: Prasterone is converted to estrogen, which is not recommended for women with a history of breast cancer.

Precautions & Warnings

  • Intrarosa 6.5 mg should be used with caution and under the supervision of a healthcare provider. Inform your doctor if you have a history of breast cancer or unexplained vaginal bleeding. Avoid use during pregnancy and breastfeeding. Store at room temperature: Keep away from moisture and heat.

Avoid Interactions

Intrarosa 6.5 mg may interact with other medications. Major Interactions (Avoid):

  • Estrogen therapies: Concurrent use with estrogen-based treatments may increase the risk of side effects.
  • Hormonal therapies: May affect the efficacy and safety of other hormonal medications.

Moderate Interactions (Monitor Closely)

  • Breast cancer treatments: Monitor for potential interactions and side effects.
  • Vaginal infections: May require additional monitoring and treatment adjustments.

Frequently Asked Questions

Intrarosa 6.5 mg is used to treat moderate to severe painful sexual intercourse (dyspareunia) in postmenopausal women. This condition is often caused by vulvar and vaginal atrophy, which results from the natural decline in estrogen levels during menopause. The medication helps improve vaginal tissue and reduce pain during intercourse.

Prasterone, the active ingredient in Intrarosa 6.5 mg, is a manmade form of dehydroepiandrosterone (DHEA). Once administered vaginally, prasterone is converted into active sex hormones, including estrogen and testosterone, in the vaginal tissues. This process helps restore the vaginal epithelium, improving lubrication and elasticity, which alleviates symptoms of vulvar and vaginal atrophy.

The usual dose of Intrarosa 6.5 mg is one vaginal insert placed into the vagina every day at bedtime. The prescriber will determine the appropriate dosage and duration of treatment based on the individual's needs and response to the medication.

Intrarosa 6.5 mg should not be used by women who are pregnant or breastfeeding. The medication is specifically indicated for postmenopausal women and is not recommended for use during pregnancy or while nursing due to potential risks to the developing fetus or infant.

To order Intrarosa 6.5 mg from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets and will ask the buyer to confirm trade or institutional credentials. The team will then reply with pricing, availability, shipping, and the necessary import paperwork.

Intrarosa 6.5 mg is the only vaginal non-estrogen treatment approved for moderate to severe painful sex due to menopause. Unlike estrogen-based therapies, it does not carry the same risks associated with estrogen use, making it a suitable option for women who cannot or prefer not to use estrogen treatments.

Intrarosa 6.5 mg should be stored at room temperature away from moisture and heat. Each applicator is for one-time use only. Empty your bladder and wash your hands before handling the vaginal insert and applicator. Use only the applicator supplied with the medication to insert the vaginal insert.

Intrarosa 6.5 mg is administered vaginally using the applicator provided with the medication. The usual dose is one insert placed into the vagina every day at bedtime. Follow the instructions provided by your healthcare provider and the medication guide for proper administration.

The most serious risks associated with Intrarosa 6.5 mg include allergic reactions, such as rash, itching, swelling, severe dizziness, or trouble breathing. Additionally, women with a history of breast cancer should avoid using this medication, as prasterone is converted to estrogen, which is not recommended for women with a history of breast cancer.

Intrarosa 6.5 mg should not be used by women who are allergic to prasterone or have unexplained vaginal bleeding that has not been checked by a healthcare provider. It is also not recommended for women who are pregnant or breastfeeding, as well as those with a history of breast cancer.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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