Product image of Ipratropium Bromide 0.03% (Ipratropium Bromide) 21mcg/spray x30ml Bottles supplied by GNH India

Ipratropium Bromide 0.03%

Active Ingredient:
Ipratropium Bromide
Form:
Bottles
Brand:
Ipratropium Bromide
Origin:
USA

Ipratropium Bromide 0.03% (Ipratropium Bromide Bottles) 21mcg/spray x30ml

Ipratropium bromide, the active ingredient in Ipratropium Bromide 0.03%, is an anticholinergic (muscarinic antagonist) presented as a 21mcg/spray in a 30ml bottle for inhalation use. It is used to treat chronic obstructive pulmonary disease (COPD), asthma, and bronchospasm in adults and children. GNH India supplies Ipratropium Bromide as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide.

GNH India is a trusted supplier of high-quality pharmaceuticals, ensuring that Ipratropium Bromide meets international standards for safety and efficacy.

Strength

21mcg/spray x30ml

Pack Size

1s

Storage

Below 25°C

Manufacturer / TM Owner

Apotex Corp.

1
Pack/s
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Indications & Clinical Uses

Ipratropium Bromide 0.03% is a bronchodilator used to manage symptoms of respiratory conditions. It is indicated for the following conditions:

  • Chronic obstructive pulmonary disease (COPD): Helps to relieve bronchospasm and improve airflow.
  • Asthma: Used to prevent bronchospasm and manage symptoms.
  • Bronchospasm: Provides relief from acute bronchospasm in conditions like chronic bronchitis and emphysema.

How It Works

  • Ipratropium bromide works by competitively antagonizing muscarinic acetylcholine receptors (M1, M3) in airway smooth muscle. This action leads to bronchodilation by inhibiting the vagally-mediated reflexes that cause bronchoconstriction and increased mucus secretion.

Side Effects

Ipratropium Bromide 0.03% may cause side effects, which can be categorized as follows:

Common Side Effects

  • Dry mouth: A frequent side effect due to anticholinergic properties.
  • Nasal dryness or irritation: Common with nasal administration.
  • Headache: May occur in some patients.
  • Nausea: A possible gastrointestinal side effect.
  • Cough: May be experienced by some users.
  • Throat irritation: Can occur with inhalation use.

Serious or Rare Side Effects

  • Allergic reactions: Rare but can include rash, itching, or swelling.
  • Worsening of narrow-angle glaucoma: Caution is advised in patients with this condition.
  • Urinary retention: Rare but possible due to anticholinergic effects.
  • Paradoxical bronchospasm: Rare but serious, requiring immediate medical attention.

Precautions & Warnings

Ipratropium Bromide 0.03% should be used with caution in certain conditions and populations. Precautions include:

  • Avoid use in patients with hypersensitivity to atropine or its derivatives: Contraindicated in these individuals.
  • Caution in patients with narrow-angle glaucoma: May worsen the condition.
  • Caution in patients with urinary retention: Due to anticholinergic effects.
  • Avoid spraying into the eyes: Can cause blurred vision or increased intraocular pressure.
  • Use with caution in patients with cardiovascular diseases: Monitor for potential cardiovascular effects.
  • Store below 25°C: Keep in the original pack, protect from moisture.

Avoid Interactions

Ipratropium Bromide 0.03% may interact with other medications, which can be categorized as follows:

Major Interactions (Avoid)

  • Other anticholinergic drugs: Increased risk of anticholinergic effects.
  • Monoclonal antibodies: Potential for increased side effects.
  • Beta-blockers: May reduce the effectiveness of ipratropium bromide.

Moderate Interactions (Monitor Closely)

  • Antihistamines: May enhance anticholinergic effects.
  • Tricyclic antidepressants: Increased risk of side effects.
  • Other bronchodilators: Monitor for increased bronchodilation effects.

Frequently Asked Questions

Ipratropium Bromide 0.03% is used to treat chronic obstructive pulmonary disease (COPD), asthma, and bronchospasm. It helps to relieve bronchospasm and improve airflow in the lungs, making it easier to breathe. The medication is administered via inhalation and works by relaxing the muscles in the airways.

Ipratropium bromide works by competitively antagonizing muscarinic acetylcholine receptors (M1, M3) in the airway smooth muscle. This action inhibits the vagally-mediated reflexes that cause bronchoconstriction and increased mucus secretion, leading to bronchodilation. By relaxing the airway muscles, it helps to improve airflow and reduce symptoms of respiratory conditions.

The usual dose of Ipratropium Bromide 0.03% is determined by a healthcare provider based on the patient's condition and response to treatment. It is typically administered as two sprays per nostril two or three times daily for the symptomatic relief of rhinorrhea associated with allergic and nonallergic perennial rhinitis in adults and children age 6 years and older.

Ipratropium Bromide is classified as a pregnancy category B drug, meaning that animal studies have not shown a risk to the fetus, but there are no adequate and well-controlled studies in pregnant women. It should be used during pregnancy only if clearly needed. For breastfeeding, it is recommended to consult a healthcare provider to weigh the benefits and potential risks.

To order Ipratropium Bromide from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets. The team will ask you to confirm your trade or institutional credentials and will reply with pricing, availability, shipping, and the import paperwork.

Ipratropium Bromide is an anticholinergic bronchodilator that works by relaxing the airway muscles. It is often used in combination with other asthma medications, such as beta-agonists, to manage symptoms. Compared to beta-agonists, it has a different mechanism of action and may be used when other medications are not effective or well-tolerated.

Ipratropium Bromide should be stored below 25°C, kept in the original pack, and protected from moisture. Avoid freezing and ensure the medication is kept out of reach of children. Proper storage helps maintain the efficacy and safety of the medication.

Ipratropium Bromide is administered via inhalation using a metered-dose inhaler or a nebulizer. The medication is sprayed into the nostrils or inhaled into the lungs, depending on the formulation. It is important to follow the instructions provided by the healthcare provider or the product label for proper administration.

The most serious risks associated with Ipratropium Bromide include allergic reactions, worsening of narrow-angle glaucoma, urinary retention, and paradoxical bronchospasm. Patients should seek immediate medical attention if they experience symptoms such as rash, itching, swelling, blurred vision, difficulty urinating, or worsening of breathing difficulties.

Ipratropium Bromide should not be used by patients with a history of hypersensitivity to atropine or its derivatives, or to any of the other ingredients in the medication. It should also be used with caution in patients with narrow-angle glaucoma, urinary retention, and cardiovascular diseases. Always consult a healthcare provider before starting any new medication.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

References

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