Product image of Ipratropium Bromide 42 ug/1 (Ipratropium Bromide) 42 ug/1 SPRAY supplied by GNH India

Ipratropium Bromide 42 ug/1

Active Ingredient:
Ipratropium Bromide
Form:
SPRAY
Brand:
Ipratropium Bromide
Origin:
USA

Ipratropium Bromide 42 ug/1 (Ipratropium Bromide SPRAY) 42 ug/1

Ipratropium bromide, the active ingredient in Ipratropium Bromide 42 µg/1, is an anticholinergic (muscarinic antagonist) presented as a 42 µg/1 nasal spray for nasal use. It is used to treat rhinorrhea associated with the common cold, seasonal allergic rhinitis, and perennial rhinitis in adults and children. GNH India supplies Ipratropium Bromide 42 µg/1 as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide.

Ipratropium bromide nasal spray is a prescription medication used to relieve runny nose (rhinorrhea) caused by certain conditions, especially seasonal allergies (hay fever) or the common cold. It comes as a metered-dose nasal spray in two strengths: 0.06% (often used short-term for colds or seasonal allergy episodes) and 0.03% (used for more chronic, year-round nasal discharge, such as in perennial allergic or non-allergic rhinitis).

Strength

42 ug/1

Pack Size

1 BOTTLE, SPRAY in 1 CARTON (0054-0046-41) / 165 SPRAY in 1 BOTTLE, SPRAY

Manufacturer / TM Owner

Hikma Pharmaceuticals USA Inc.

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Indications & Clinical Uses

Ipratropium bromide nasal spray is indicated for the symptomatic relief of rhinorrhea associated with the common cold, seasonal allergic rhinitis, and perennial rhinitis. It is not a decongestant or antihistamine and does not relieve nasal congestion, sneezing, or postnasal drip.

  • Common cold: Reduces nasal discharge associated with the common cold.
  • Seasonal allergic rhinitis: Alleviates runny nose symptoms during allergy seasons.
  • Perennial rhinitis: Manages chronic nasal discharge due to allergic or non-allergic causes.

How It Works

  • Ipratropium bromide works by blocking the action of acetylcholine on muscarinic receptors in the nasal mucosa. This reduces the amount of mucus produced by the nasal glands, thereby decreasing nasal secretions and providing relief from a runny nose. Its targeted action helps to dry up the nasal passages without affecting the sense of smell or causing drowsiness.

Side Effects

Side effects of ipratropium bromide nasal spray can vary in severity. Common Side Effects:

  • Dry or bloody nose
  • Headache
  • Dry mouth or throat
  • Throat irritation
  • Bad taste in the mouth
  • Dizziness
  • Constipation

Serious or Rare Side Effects

  • Blurred vision or eye pain (if sprayed in the eyes)
  • Narrow-angle glaucoma (in susceptible individuals)
  • Severe nasal irritation or ulceration
  • Allergic reactions such as rash, itching, or swelling

Precautions & Warnings

  • Ipratropium bromide nasal spray should be used with caution in certain populations and conditions. Always follow the advice of a healthcare provider. Avoid spraying in the eyes to prevent blurred vision or eye pain. Patients with narrow-angle glaucoma, urinary retention, or severe heart conditions should use this medication with caution. Store at room temperature away from moisture and heat. Keep the cap tightly closed when not in use. Do not allow the medicine to freeze.

Avoid Interactions

Ipratropium bromide nasal spray can interact with other medications, potentially affecting its efficacy or increasing the risk of side effects. Major Interactions (Avoid):

  • Other anticholinergic medications: Increased risk of side effects such as dry mouth, blurred vision, and urinary retention.
  • Monoclonal antibodies: Potential for increased anticholinergic effects.

Moderate Interactions (Monitor Closely)

  • Beta-blockers: May increase the risk of bronchospasm in patients with asthma or COPD.
  • Antihistamines: May enhance anticholinergic effects.
  • Decongestants: May increase the risk of dryness and irritation in the nasal passages.

Frequently Asked Questions

Ipratropium Bromide 42 µg/1 is used to treat rhinorrhea (runny nose) associated with the common cold, seasonal allergic rhinitis, and perennial rhinitis. It works by reducing the amount of mucus produced in the nasal passages, providing relief from a runny nose. It is not a decongestant or antihistamine and does not relieve nasal congestion, sneezing, or postnasal drip.

Ipratropium bromide is an anticholinergic medication that blocks the action of acetylcholine on muscarinic receptors in the nasal mucosa. By doing so, it reduces the production of mucus in the nasal glands, which helps to decrease nasal secretions and alleviate symptoms of a runny nose. Its targeted action helps to dry up the nasal passages without affecting the sense of smell or causing drowsiness.

The usual dose of Ipratropium Bromide 42 µg/1 is determined by a healthcare provider based on the condition being treated. For the common cold, it is typically used as 2 sprays in each nostril 3 to 4 times a day. For seasonal allergic rhinitis, it is usually 2 sprays in each nostril 4 times a day. For perennial rhinitis, it is 2 sprays in each nostril 2 to 3 times a day.

Ipratropium bromide is classified as a pregnancy category C medication, meaning that it should be used during pregnancy only if the potential benefits outweigh the risks. It is not known whether ipratropium bromide is excreted in human milk. Women who are pregnant or breastfeeding should consult their healthcare provider before using this medication.

To order Ipratropium Bromide 42 µg/1 from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets. The team will ask you to confirm your trade or institutional credentials and will reply with pricing, availability, shipping, and the import paperwork.

Ipratropium bromide is different from other nasal decongestants because it specifically targets the mucus-producing glands in the nasal passages. Unlike decongestants, which shrink blood vessels to reduce congestion, ipratropium bromide reduces the production of mucus, making it particularly effective for a runny nose. It does not relieve nasal congestion, sneezing, or postnasal drip, so it is often used in combination with other medications for comprehensive symptom relief.

Ipratropium Bromide 42 µg/1 should be stored at room temperature away from moisture and heat. Keep the cap tightly closed when not in use. Do not allow the medicine to freeze. Proper storage ensures the medication remains effective and safe to use.

Ipratropium Bromide 42 µg/1 is administered as a nasal spray. Gently blow your nose before using the medication. Spray the medication into the nose as directed by your healthcare provider, usually 3 or 4 times a day in each nostril. Avoid spraying it in your eyes, as it can cause blurred vision or eye pain.

The most serious risks associated with Ipratropium Bromide include blurred vision or eye pain if the spray gets into the eyes, which can potentially trigger an acute attack of narrow-angle glaucoma. Severe nasal irritation or ulceration and allergic reactions such as rash, itching, or swelling are also possible. If you experience any of these symptoms, seek medical advice immediately.

Ipratropium Bromide 42 µg/1 should not be used by individuals who are allergic to ipratropium bromide or any of the other ingredients in the medication. It should be used with caution in patients with narrow-angle glaucoma, urinary retention, or severe heart conditions. Always consult a healthcare provider before using this medication, especially if you have any pre-existing medical conditions or are taking other medications.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

References

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