JANUMET XR 100 mg/1 (Sitagliptin and Metformin Hydrochloride TABLET, FILM COATED, EXTENDED RELEASE) 100 mg/1

JANUMET XR 100 mg/1 combines sitagliptin and metformin hydrochloride for extended-release blood sugar management. This oral medication supports glucose control in adults with type 2 diabetes. Learn about its uses, effects, and precautions.

Strength

100 mg/1

Pack Size

2 BOTTLE in 1 CARTON (0006-0081-14) / 7 TABLET, FILM COATED, EXTENDED RELEASE in 1 BOTTLE (0006-008

Manufacturer / TM Owner

Merck Sharp & Dohme LLC

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Indications & Clinical Uses

JANUMET XR 100 mg/1 is primarily used to manage blood sugar levels in adults with type 2 diabetes. This extended-release tablet combines sitagliptin, a DPP-4 inhibitor, and metformin hydrochloride, a biguanide, to improve glycemic control. People often ask, 'What is JANUMET XR used for?' It is typically prescribed as part of a broader diabetes management plan, including diet and exercise.

Side Effects

Common effects of JANUMET XR 100 mg/1 may include gastrointestinal discomfort, such as diarrhea or nausea, particularly when first starting the medication. Some users report headaches or upper respiratory infections. These effects vary and are not experienced by everyone. Always consult a healthcare provider for personalized advice.

Precautions & Warnings

Handle JANUMET XR 100 mg/1 with care, especially if you have kidney or liver issues. Avoid alcohol while taking this medication, as it can increase the risk of lactic acidosis. Store the tablets at room temperature, and follow the prescribed dosage to minimize potential side effects.

Avoid Interactions

JANUMET XR 100 mg/1 may interact with certain medications, including other diabetes drugs, diuretics, and some antibiotics. Alcohol can also interact negatively with metformin, increasing the risk of lactic acidosis. Always inform your healthcare provider about all medications you are taking to avoid potential interactions.

Frequently Asked Questions

JANUMET XR 100 mg/1 is used to manage blood sugar levels in adults with type 2 diabetes. It combines sitagliptin and metformin hydrochloride to improve glycemic control.

Store JANUMET XR 100 mg/1 at room temperature, away from moisture and heat. Keep the tablets in their original packaging until ready to use.

Common side effects may include gastrointestinal discomfort, headaches, and upper respiratory infections. These effects vary and are not experienced by everyone.

Avoid alcohol while taking JANUMET XR 100 mg/1, as it can increase the risk of lactic acidosis, a serious condition.

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule.

Editorial & Trust Signals

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical wholesaler & exporter

Last updated: 17 Jun 2026

References

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