JANUMET XR 1000 mg/1 (Sitagliptin and Metformin Hydrochloride TABLET, FILM COATED, EXTENDED RELEASE) 1000 mg/1

JANUMET XR 1000 mg/1 combines sitagliptin and metformin hydrochloride for blood sugar management. This extended-release tablet is designed for oral use and is manufactured by Merck Sharp & Dohme LLC in the USA.

Strength

1000 mg/1

Pack Size

60 TABLET, FILM COATED, EXTENDED RELEASE in 1 BOTTLE (0006-0080-61)

Manufacturer / TM Owner

Merck Sharp & Dohme LLC

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Indications & Clinical Uses

JANUMET XR 1000 mg/1 is typically used to help manage blood sugar levels in adults with type 2 diabetes. It combines two active ingredients, sitagliptin and metformin hydrochloride, to support glucose control. This medication is often prescribed as part of a broader treatment plan that includes diet and exercise. People often ask, 'What is JANUMET XR used for?' and the primary use is to aid in the management of type 2 diabetes.

Side Effects

Common effects of JANUMET XR 1000 mg/1 may include gastrointestinal discomfort, such as nausea or diarrhea, especially when first starting the medication. Some users may also experience headaches or a metallic taste in the mouth. These effects are generally mild and temporary, but if they persist or worsen, it is important to consult a healthcare provider.

Precautions & Warnings

JANUMET XR 1000 mg/1 should be taken exactly as directed by a healthcare provider. It is important to follow the prescribed dosage and not to crush or chew the extended-release tablets. This medication should be stored at room temperature, away from moisture and heat. Always inform your healthcare provider about any other medications you are taking to avoid potential interactions.

Avoid Interactions

JANUMET XR 1000 mg/1 may interact with certain medications, including other diabetes drugs, antibiotics, and some heart or blood pressure medications. Alcohol can also affect the effectiveness of this medication and should be avoided. It is important to discuss all current medications with your healthcare provider to ensure safe and effective use of JANUMET XR.

Frequently Asked Questions

JANUMET XR 1000 mg/1 is used to help manage blood sugar levels in adults with type 2 diabetes.

JANUMET XR 1000 mg/1 should be taken orally, with a meal, and swallowed whole without crushing or chewing.

Common side effects may include gastrointestinal discomfort, headaches, and a metallic taste in the mouth.

Alcohol can affect the effectiveness of JANUMET XR 1000 mg/1 and should be avoided.

If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. Do not double the dose to catch up.

Editorial & Trust Signals

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical wholesaler & exporter

Last updated: 17 Jun 2026

References

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