JANUMET XR 50 mg/1 (Sitagliptin and Metformin Hydrochloride TABLET, FILM COATED, EXTENDED RELEASE) 50 mg/1

Janumet XR 50 mg/1 combines sitagliptin and metformin hydrochloride for extended-release blood sugar management. This oral medication supports glucose control in adults with type 2 diabetes.

Strength

50 mg/1

Pack Size

180 TABLET, FILM COATED, EXTENDED RELEASE in 1 BOTTLE (0006-0080-62)

Manufacturer / TM Owner

Merck Sharp & Dohme LLC

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Indications & Clinical Uses

Janumet XR 50 mg/1 is primarily used to improve glycemic control in adults with type 2 diabetes. This extended-release tablet combines sitagliptin, a DPP-4 inhibitor, and metformin hydrochloride, a biguanide. Together, they work to lower blood sugar levels by enhancing insulin sensitivity and reducing glucose production. People often ask, 'What is Janumet XR used for?' It is typically prescribed as part of a comprehensive diabetes management plan, including diet and exercise.

Side Effects

Common effects of Janumet XR 50 mg/1 may include gastrointestinal discomfort, such as nausea, diarrhea, or abdominal pain. Some users also report headache or upper respiratory tract infection. These effects vary by individual and are not experienced by everyone. Always consult a healthcare provider for personalized advice.

Precautions & Warnings

Janumet XR 50 mg/1 should be handled with care, especially for those with kidney or liver issues. It is important to stay hydrated and monitor blood sugar levels regularly. Avoid alcohol while taking this medication, as it may increase the risk of lactic acidosis. Always follow the guidance of a healthcare professional.

Avoid Interactions

Janumet XR 50 mg/1 may interact with certain medications, including diuretics, corticosteroids, and some antibiotics. Alcohol can also increase the risk of side effects. Always inform your healthcare provider about all medications you are taking to avoid potential interactions. CYP inhibitors and inducers may affect how this medication works.

Frequently Asked Questions

Janumet XR 50 mg/1 is used to improve blood sugar control in adults with type 2 diabetes. It combines sitagliptin and metformin hydrochloride to help manage glucose levels.

Janumet XR 50 mg/1 is an oral medication that should be taken exactly as prescribed by a healthcare provider. It is typically taken once daily with a meal.

Common side effects may include gastrointestinal discomfort, nausea, diarrhea, and headache. Always consult a healthcare provider for personalized advice.

Janumet XR 50 mg/1 may interact with certain medications. Always inform your healthcare provider about all medications you are taking to avoid potential interactions.

Janumet XR 50 mg/1 should be used with caution in individuals with kidney or liver issues. Always consult a healthcare provider before starting this medication.

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Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical wholesaler & exporter

Last updated: 17 Jun 2026

References

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