Product image of Jublia 10 % (Efinaconazole) 10 % SOLUTION supplied by GNH India

Jublia 10 %

Active Ingredient:
Efinaconazole
Form:
SOLUTION
Brand:
JUBLIA
Origin:
CANADA

Jublia 10 % (Efinaconazole SOLUTION) 10 %

Efinaconazole, the active ingredient in JUBLIA, is an azole antifungal presented as a 10% solution for topical use. It is indicated for the treatment of onychomycosis (toenail fungus) caused by Trichophyton rubrum and Trichophyton mentagrophytes. GNH India supplies JUBLIA as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide.

JUBLIA is a prescription medication designed to target and eliminate fungal infections in the toenails. It is applied directly to the affected area and works by disrupting the fungal cell membrane, leading to the death of the fungus.

Strength

10 %

Manufacturer / TM Owner

BAUSCH HEALTH, CANADA INC.

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Indications & Clinical Uses

JUBLIA is an antifungal medication used to treat toenail fungal infections. It is specifically indicated for onychomycosis caused by certain types of fungi.

  • Onychomycosis of toenails: Treats fungal infections in the toenails caused by Trichophyton rubrum and Trichophyton mentagrophytes.
  • Topical application: Applied directly to the affected toenail and surrounding skin to eliminate the fungus.
  • Long-term treatment: Requires consistent application over several months to ensure the infection is fully cleared.

How It Works

  • Efinaconazole works by inhibiting fungal lanosterol 14α-demethylase, a key enzyme in the synthesis of ergosterol, a crucial component of fungal cell membranes. By disrupting ergosterol synthesis, efinaconazole compromises the integrity of the fungal cell membrane, leading to the death of the fungal cells.

Side Effects

JUBLIA may cause various side effects, ranging from common to serious.

Common Side Effects

  • Ingrown toenail: May occur at the site of application.
  • Application-site dermatitis: Redness, itching, or swelling around the treated area.
  • Application-site vesicles: Small blisters or bumps at the application site.
  • Application-site pain: Discomfort or pain where the medication is applied.

Serious or Rare Side Effects

  • Severe allergic reactions: Rash, itching, swelling (especially of the face/tongue/throat), severe dizziness, or trouble breathing.
  • Severe irritation: Intense redness, itching, or swelling that does not subside.
  • Blisters: Formation of blisters at the application site.

Precautions & Warnings

JUBLIA should be used with caution and under the guidance of a healthcare professional.

  • Pregnancy: Use only if the potential benefit justifies the potential risk to the fetus.
  • Breastfeeding: Use with caution, as the safety in nursing women is not established.
  • Pediatric use: Safety and effectiveness in children under 6 years of age have not been established.
  • Application site: Avoid contact with eyes, mouth, or vagina.
  • Flammability: The solution is flammable; avoid heat and flame while applying.
  • Storage: Store at room temperature: Keep the bottle upright and tightly closed, away from heat or flame, and protect from light and moisture.

Avoid Interactions

JUBLIA may interact with other medications, requiring careful monitoring.

Major Interactions (Avoid)

  • None identified.

Moderate Interactions (Monitor Closely)

  • Other topical medications: Avoid using other topical treatments on the same area without consulting a healthcare professional.
  • Systemic antifungals: Concurrent use with other systemic antifungals should be monitored for potential interactions.
  • Immunosuppressants: May require careful monitoring when used together.

Frequently Asked Questions

JUBLIA is a topical antifungal medication used to treat onychomycosis, which is a fungal infection of the toenails caused by Trichophyton rubrum and Trichophyton mentagrophytes. It is applied directly to the affected toenail and surrounding skin to eliminate the fungus.

Efinaconazole works by inhibiting fungal lanosterol 14α-demethylase, a key enzyme in the synthesis of ergosterol, a crucial component of fungal cell membranes. By disrupting ergosterol synthesis, efinaconazole compromises the integrity of the fungal cell membrane, leading to the death of the fungal cells.

The usual dose of JUBLIA is one drop applied to the affected toenail once a day, preferably at bedtime. The treatment duration is typically 48 weeks. However, the prescriber will determine the exact dosage and duration based on the individual's condition.

JUBLIA should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It should be used with caution in nursing women, as the safety in breastfeeding is not established. Always consult a healthcare professional before using JUBLIA during pregnancy or breastfeeding.

To order JUBLIA from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets and will ask the buyer to confirm trade or institutional credentials. The team will then reply with pricing, availability, shipping, and the import paperwork.

JUBLIA is specifically formulated for the treatment of toenail fungal infections and is applied topically. Compared to oral antifungal medications, JUBLIA targets the infection directly at the site, reducing the risk of systemic side effects. However, the choice of treatment depends on the individual's condition and should be determined by a healthcare professional.

JUBLIA should be stored at room temperature, with the bottle upright and tightly closed. Keep it away from heat or flame, as the solution is flammable. Protect the medication from light and moisture, and keep it out of the reach of children.

JUBLIA is applied using the provided brush applicator. Clean and dry the affected toenail before application. Apply one drop to the surface of each affected toenail once a day, preferably at bedtime. Allow the solution to dry completely before touching the area with sheets, socks, or other clothing.

The most serious risks associated with JUBLIA include severe allergic reactions, such as rash, itching, swelling (especially of the face/tongue/throat), severe dizziness, or trouble breathing. If any of these symptoms occur, seek medical attention immediately.

JUBLIA should not be used by individuals who are allergic to efinaconazole or any of the inactive ingredients in the medication. It should also be used with caution in children under 6 years of age, as its safety and effectiveness in this age group have not been established. Always consult a healthcare professional before using JUBLIA.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

References

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