Product image of KENALOG-40 40 mg/mL (Triamcinolone Acetonide) 40 mg/mL INJECTION, SUSPENSION supplied by GNH India

KENALOG-40 40 mg/mL

Active Ingredient:
Triamcinolone Acetonide
Form:
INJECTION, SUSPENSION
Brand:
KENALOG-40
Origin:
USA

KENALOG-40 40 mg/mL (Triamcinolone Acetonide INJECTION, SUSPENSION) 40 mg/mL

Triamcinolone acetonide, the active ingredient in Kenalog-40, is a corticosteroid presented as a 40 mg/mL injection, suspension for intra-articular or intramuscular use. It is used to treat inflammatory conditions such as osteoarthritis, rheumatoid arthritis, bursitis, tendinitis, and synovitis in adults and children over 1 month old. GNH India supplies Kenalog-40 as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide.

Kenalog-40 is a synthetic glucocorticoid corticosteroid with anti-inflammatory and immunosuppressive properties. It is administered by healthcare professionals to relieve pain and inflammation in affected joints or muscles.

Strength

40 mg/mL

Pack Size

1 VIAL, MULTI-DOSE in 1 CARTON (0003-0293-20) / 5 mL in 1 VIAL, MULTI-DOSE

Manufacturer / TM Owner

E.R. Squibb & Sons, L.L.C.

1
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Indications & Clinical Uses

Kenalog-40 is used to treat various inflammatory conditions by reducing inflammation and suppressing the immune response. Common uses include:

  • Osteoarthritis: Reduces pain and inflammation in the joints.
  • Rheumatoid arthritis: Helps manage joint inflammation and pain.
  • Bursitis: Alleviates inflammation in the bursae, the small fluid-filled sacs that cushion the bones, tendons, and muscles near the joints.
  • Tendinitis: Reduces inflammation in the tendons.
  • Synovitis: Helps manage inflammation of the synovial membrane, which lines joints.

How It Works

  • Triamcinolone acetonide works by binding to intracellular glucocorticoid receptors, which then modulate gene transcription. This action leads to anti-inflammatory and immunosuppressive effects by inhibiting the production of inflammatory cytokines and reducing the activity of immune cells.

Side Effects

Kenalog-40 may cause various side effects, ranging from mild to serious. Common Side Effects:

  • Increased appetite
  • Fluid retention
  • Mild, short-term increase in blood sugar
  • Increased risk of infection

Serious or Rare Side Effects

  • Increased risk of infection
  • Joint damage
  • Changes in mood or personality
  • Osteoporosis
  • Eye problems, including cataracts and glaucoma
  • Adrenal insufficiency (low adrenal gland function)
  • Cushing syndrome
  • Low blood potassium level
  • Low blood calcium level
  • High blood pressure
  • Increased blood sugar, which can lead to type 2 diabetes

Precautions & Warnings

Kenalog-40 should be used with caution and under the supervision of a healthcare professional. Important precautions include:

  • Avoid use in neonates: This drug should not be used in neonates.
  • Allergic reactions: Seek immediate medical attention if signs of an allergic reaction occur.
  • Adrenal insufficiency: Monitor for symptoms of adrenal gland that is less active than normal.
  • Eye problems: Regular eye examinations are recommended to monitor for cataracts and glaucoma.
  • Bone density: Regular monitoring for changes in bone density is advised.
  • Store below 25°C: Keep in the original pack, protect from moisture.

Avoid Interactions

Kenalog-40 may interact with other medications, potentially affecting its efficacy or increasing the risk of side effects. Major Interactions (Avoid):

  • Live vaccines: Avoid concurrent use with live vaccines due to the risk of infection.
  • Nonsteroidal anti-inflammatory drugs (NSAIDs): Increased risk of gastrointestinal side effects.

Moderate Interactions (Monitor Closely)

  • Anticoagulants: Monitor for changes in blood clotting.
  • Antidiabetic drugs: Monitor blood sugar levels closely.
  • Antihypertensives: Monitor blood pressure regularly.

Frequently Asked Questions

Kenalog-40 is used to treat various inflammatory conditions, including osteoarthritis, rheumatoid arthritis, bursitis, tendinitis, and synovitis. It helps reduce pain and inflammation in affected joints or muscles.

Triamcinolone acetonide works by binding to intracellular glucocorticoid receptors, which then modulate gene transcription. This action leads to anti-inflammatory and immunosuppressive effects by inhibiting the production of inflammatory cytokines and reducing the activity of immune cells.

The dose of Kenalog-40 is determined by a healthcare professional based on the patient's condition, age, and response to treatment. It is important to follow the prescribed dosage and administration instructions provided by your doctor.

Kenalog-40 is classified as a pregnancy category C drug, meaning it should be used during pregnancy only if the potential benefits outweigh the risks. It is not known whether Triamcinolone Acetonide passes into breast milk, so caution is advised for breastfeeding mothers. Consult your healthcare provider for personalized advice.

To order Kenalog-40 from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets and will ask the buyer to confirm trade or institutional credentials. The team will reply with pricing, availability, shipping, and the import paperwork.

Kenalog-40 is a synthetic glucocorticoid corticosteroid with a prolonged duration of action. It is similar to other corticosteroids like methylprednisolone and prednisone but may have a different duration and intensity of effect. The choice of corticosteroid depends on the specific condition being treated and the patient's response.

Kenalog-40 should be stored below 25°C, kept in the original pack, and protected from moisture. It should not be frozen or shaken. Always follow the storage instructions provided by the manufacturer to ensure the medication's effectiveness and safety.

Kenalog-40 is administered by a healthcare professional as an injection into the affected joint (intra-articular) or muscle (intramuscular). The administration should be performed under sterile conditions to minimize the risk of infection.

The most serious risks associated with Kenalog-40 include increased risk of infection, joint damage, changes in mood or personality, osteoporosis, eye problems (such as cataracts and glaucoma), adrenal insufficiency, Cushing syndrome, low blood potassium and calcium levels, high blood pressure, and increased blood sugar levels.

Kenalog-40 should not be used by individuals who are allergic to Triamcinolone Acetonide or any of the excipients in the formulation. It should also be used with caution in patients with systemic fungal infections, ocular herpes simplex, and certain other conditions. Always consult your healthcare provider for personalized advice.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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