Ketonal (Ketoprofen)

Ketoprofen inhibits both cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, decreasing the synthesis of prostaglandins that mediate inflammation, pain and fever. By reducing prostaglandin levels at the site of application, the drug provides local anti‑inflammatory and analgesic effects without significant systemic exposure when used as directed.

The specific amount of Ketonal to apply, frequency and duration are determined by the prescribing healthcare professional based on the severity of the condition, the area of skin treated and patient factors. Patients should follow the prescriber’s instructions and the product label.

Safety of topical ketoprofen during pregnancy or lactation has not been fully established. It should be used only if the potential benefit outweighs the risk and after consultation with a qualified healthcare provider. Generally, alternative treatments are preferred for pregnant or nursing women.

To place an order, submit an enquiry on the Ketonal product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ketonal delivers ketoprofen directly to the skin, offering targeted relief with lower systemic exposure compared with oral NSAIDs such as ibuprofen or diclofenac. This topical route can reduce the risk of gastrointestinal side effects, but efficacy depends on proper application and may be less suitable for deep‑seated pain.

Store Ketonal at room temperature, below 25 °C, in its original packaging. Keep the container tightly closed, protect it from moisture, direct sunlight and excessive heat to maintain product stability and effectiveness throughout its shelf life.

Apply a thin layer of the gel or cream to the affected skin area, gently massaging it until absorbed. The usual frequency is as directed by the prescriber, often two to four times daily, and the treatment period should not exceed the duration recommended on the label.

Although applied locally, ketoprofen can be absorbed systemically and may cause serious adverse reactions such as severe skin reactions (e.g., Stevens‑Johnson syndrome), allergic angioedema, gastrointestinal bleeding, renal impairment or hepatic injury. Immediate medical attention is required if any of these symptoms occur.

Ketonal should be avoided in individuals with known hypersensitivity to ketoprofen or other NSAIDs, in patients with active skin infections, open wounds or severe dermatitis at the application site, and in those with a history of severe cardiovascular, renal or hepatic disease unless specifically advised by a physician.