Ketonal (Ketoprofen)

Ketoprofen works by blocking the activity of cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for producing prostaglandins. Prostaglandins amplify pain signals and promote inflammation, so their reduction leads to decreased swelling, pain perception, and fever, providing therapeutic relief.

The specific dose of Ketonal is determined by the prescribing healthcare professional based on the patient’s condition, weight, renal and hepatic function, and the route of administration. Only a qualified prescriber should set the dosage and frequency.

The safety of ketoprofen in pregnancy and lactation has not been definitively established. It is generally avoided during the third trimester because of potential fetal cardiovascular effects, and caution is advised for nursing mothers. Physicians should evaluate risks versus benefits before prescribing.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and necessary import documentation.

Ketoprofen is generally more potent on a milligram‑per‑milligram basis than ibuprofen and has a longer half‑life, allowing less frequent dosing. Both share similar mechanisms (COX inhibition) and safety profiles, but ketoprofen may carry a slightly higher risk of gastrointestinal irritation, requiring careful patient selection.

Ketonal should be stored below 25 °C (77 °F) in its original packaging. Protect the product from direct light, moisture and extreme temperature fluctuations. Do not freeze the injection solution, and keep it out of reach of children.

Ketonal is supplied as a sterile injectable solution for intramuscular (IM) or intravenous (IV) administration. The injection is performed by a qualified healthcare professional under aseptic conditions, using the dose and route prescribed by the treating physician.

The most serious risks include severe gastrointestinal bleeding or ulceration, acute kidney injury, cardiovascular events such as heart attack or stroke, and life‑threatening allergic reactions (anaphylaxis). Patients should be monitored closely for signs of these complications, especially if they have pre‑existing risk factors.

Ketonal is contraindicated in patients with known hypersensitivity to ketoprofen or other NSAIDs, active gastrointestinal ulceration, severe renal or hepatic impairment, and in the third trimester of pregnancy. It should also be avoided in individuals with uncontrolled hypertension or a history of cardiovascular thrombotic events unless specifically directed by a physician.