Ketonal (Ketoprofen)

Ketoprofen works by non‑selectively blocking the COX‑1 and COX‑2 enzymes, which reduces the production of prostaglandins—chemical mediators that cause inflammation, pain, and fever. Lower prostaglandin levels lead to decreased swelling and pain perception.

The exact dose of Ketonal is determined by the prescribing clinician based on the patient’s condition, severity of symptoms, and renal or hepatic function. Healthcare professionals follow local guidelines and adjust the amount and frequency as needed.

Safety data for ketoprofen during pregnancy and lactation are limited. It is generally avoided, especially in the third trimester, because of potential fetal risks. Breastfeeding mothers should consult their physician before using the product.

To order Ketonal, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if required) and necessary import documentation.

Ketonal (ketoprofen) offers a potent anti‑inflammatory effect comparable to diclofenac and ibuprofen, but its injectable form provides faster pain relief for severe acute conditions. Choice of NSAID depends on the clinical scenario, patient tolerance, and risk‑benefit assessment made by the prescriber.

Ketonal should be stored at ambient temperature, below 25 °C, in its original container. Protect the vial from moisture, direct sunlight and physical shock. Do not freeze. Inspect the solution for particulate matter before use.

Ketonal is supplied as a sterile injectable solution for intramuscular (IM) or intravenous (IV) injection. The healthcare professional selects the appropriate route, prepares the dose under aseptic conditions, and administers it according to institutional protocols.

Serious risks include gastrointestinal bleeding or ulcer perforation, acute kidney injury, severe allergic reactions such as anaphylaxis, and liver toxicity. Patients should be monitored for signs of bleeding, renal dysfunction, or hypersensitivity, and therapy should be stopped if these occur.

Ketonal is contraindicated in individuals with known hypersensitivity to ketoprofen or other NSAIDs, active peptic ulcer disease, severe renal or hepatic impairment, and in patients receiving anticoagulant therapy where bleeding risk is high. It should also be avoided in late pregnancy unless clearly indicated.