Ketonal (Ketoprofen)

Ketoprofen works by reversibly inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2, which are essential for the synthesis of prostaglandins. By lowering prostaglandin levels, it diminishes the inflammatory response, reduces pain signaling, and helps control fever.

The dosage of Ketonal is individualized by the prescribing clinician based on the patient’s condition, severity of symptoms, and overall health status. The prescriber determines the appropriate strength, frequency, and duration of treatment.

Safety data for ketoprofen in pregnancy and lactation are limited. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and only under medical supervision. Women who are pregnant, planning pregnancy, or breastfeeding should discuss alternatives with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity of Ketonal. GNH India works with hospitals, pharmacies, and procurement teams worldwide, and will request verification of trade or institutional credentials before providing pricing, availability, shipping details, and any necessary import documentation.

Ketoprofen generally offers a longer duration of analgesic effect compared with ibuprofen, allowing for less frequent dosing in some patients. Both belong to the NSAID class and share similar mechanisms, but ketoprofen may have a slightly higher risk of gastrointestinal irritation. Choice of agent depends on individual patient tolerance, therapeutic goals, and physician preference.

Ketonal suppositories should be stored below 25 °C in their original packaging, protected from moisture and direct sunlight. Do not freeze the product. Keep out of reach of children and ensure the packaging remains intact until use.

Ketonal is supplied as a rectal suppository. The patient should lie on their side with the lower leg drawn toward the abdomen, gently insert the suppository into the rectum, and remain in that position for a few minutes to ensure proper absorption. Hand hygiene before and after insertion is recommended.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis or Stevens‑Johnson syndrome, renal impairment, and cardiovascular events like myocardial infarction or stroke. Patients should seek immediate medical attention if they experience symptoms such as black stools, severe abdominal pain, rash, swelling, or sudden chest discomfort.

Ketonal should be avoided in individuals with known hypersensitivity to ketoprofen or other NSAIDs, active gastrointestinal ulceration, severe renal or hepatic impairment, uncontrolled hypertension, and in patients with a history of cardiovascular thrombotic events unless specifically directed by a physician.