Ketonal (Ketoprofen)

Ketoprofen works by non‑selectively inhibiting the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which reduces the synthesis of prostaglandins. Lower prostaglandin levels diminish inflammation, pain signalling, and fever, providing both analgesic and anti‑inflammatory benefits at peripheral and central sites.

The specific dose and duration of Ketonal are determined by the prescribing clinician based on the individual’s condition, severity of symptoms, and overall health status. Healthcare professionals adjust the regimen to achieve the desired therapeutic effect while minimizing risk.

The safety of ketoprofen in pregnancy and lactation has not been definitively established. It is generally advised to avoid use unless clearly needed and prescribed by a qualified healthcare provider. Women who are pregnant, planning pregnancy, or breastfeeding should discuss alternatives with their doctor.

To order Ketonal, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Ketonal (ketoprofen) is comparable to other NSAIDs such as ibuprofen or diclofenac but offers a slightly stronger COX‑1 inhibition, which may provide more potent analgesia for certain inflammatory conditions. However, the increased COX‑1 activity can also raise the risk of gastrointestinal side effects, so individual risk profiles guide drug selection.

Ketonal suppositories should be stored at room temperature, below 25 °C, in the original packaging to protect them from moisture and excessive heat. Keep the product out of reach of children and avoid exposure to direct sunlight or humidity that could compromise the dosage form.

Ketonal is supplied as a rectal suppository. The suppository is inserted into the rectum, preferably after bowel movements, and allowed to dissolve completely. Administration should follow the prescriber’s instructions regarding timing, frequency and any necessary precautions such as positioning.

Serious adverse events associated with Ketonal include gastrointestinal ulceration or bleeding, acute renal impairment, severe hypersensitivity reactions such as Stevens‑Johnson syndrome or anaphylaxis, and significant hepatic injury. Patients should seek immediate medical attention if they experience signs of bleeding, sudden kidney problems, rash, or breathing difficulties.

Ketonal should be avoided in individuals with known hypersensitivity to ketoprofen or other NSAIDs, active gastrointestinal ulcer or bleeding, severe renal or hepatic impairment, uncontrolled heart failure, and in patients who are in the third trimester of pregnancy. Contra‑indications are confirmed by the prescribing clinician before therapy begins.