Leucovorin Calcium 100 mg/10mL (Leucovorin Calcium INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION) 100 mg/10mL

Leucovorin calcium 100 mg/10mL is a lyophilized powder for solution, used primarily in medical treatments. This injectable form is designed for intramuscular or intravenous administration, offering a versatile option for healthcare professionals.

Strength

100 mg/10mL

Pack Size

1 VIAL in 1 CARTON (25021-814-30) / 10 mL in 1 VIAL

Manufacturer / TM Owner

Sagent Pharmaceuticals

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Indications & Clinical Uses

Leucovorin calcium is commonly used to counteract the effects of folic acid antagonists, such as methotrexate, in cancer treatments. It plays a crucial role in enhancing the effectiveness of certain chemotherapy regimens. Leucovorin calcium 100 mg/10mL is often utilized in protocols where folate metabolism is disrupted, supporting cellular function and reducing toxicity.

Side Effects

When administered, leucovorin calcium works by replenishing folate levels in the body, which can help mitigate side effects from certain medications. Patients may experience improved tolerance to treatment regimens that involve folic acid antagonists. The specific effects can vary based on individual health conditions and the context of use.

Precautions & Warnings

Leucovorin calcium should be handled with care, ensuring proper storage and preparation to maintain its efficacy. It is essential to follow healthcare provider instructions for administration to avoid potential complications. Patients with known allergies to any components of the solution should exercise caution.

Avoid Interactions

Leucovorin calcium may interact with other medications, particularly those that affect folate metabolism. It is important to inform healthcare providers about all current medications to avoid adverse interactions. Alcohol and certain supplements might also influence the effectiveness of leucovorin calcium.

Frequently Asked Questions

Leucovorin calcium is primarily used to counteract the effects of folic acid antagonists and to support certain chemotherapy treatments.

Leucovorin calcium 100 mg/10mL is administered via intramuscular or intravenous injection, following proper medical guidelines.

Leucovorin calcium helps replenish folate levels, which can improve tolerance to certain medications and reduce side effects.

Yes, it is important to follow healthcare provider instructions for administration and to inform them of any allergies or current medications.

Yes, leucovorin calcium may interact with medications that affect folate metabolism, so it is crucial to inform healthcare providers about all current treatments.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated: 29 Jul 2026

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