Leucovorin Calcium 50 mg/5mL (Leucovorin Calcium INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION) 50 mg/5mL

Leucovorin Calcium 50 mg/5mL is a lyophilized powder for solution, used for various medical purposes. This product by Hikma Pharmaceuticals USA Inc. is administered intramuscularly or intravenously.

Strength

50 mg/5mL

Pack Size

1 VIAL in 1 BOX (0143-9555-01) / 5 mL in 1 VIAL

Manufacturer / TM Owner

Hikma Pharmaceuticals USA Inc.

Select Quantity

Pack/s

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Indications & Clinical Uses

Leucovorin Calcium is commonly used to counteract the effects of folate antagonists, such as methotrexate, in cancer treatments. It is also used to treat folate deficiencies and to enhance the effectiveness of certain chemotherapy drugs. Leucovorin Calcium 50 mg/5mL is often administered to reduce the toxicity of high-dose methotrexate therapy. The primary use of Leucovorin Calcium is to restore folate levels in the body, which can be depleted by certain medications or conditions.

Side Effects

Leucovorin Calcium works by providing a form of folic acid that the body can use to produce red blood cells and maintain healthy cell function. It helps to counteract the side effects of drugs that interfere with folate metabolism, such as methotrexate. Common effects include improved folate levels and reduced toxicity from certain chemotherapy treatments. Leucovorin Calcium 50 mg/5mL is designed to be reconstituted and administered as directed by a healthcare provider.

Precautions & Warnings

Leucovorin Calcium should be handled with care and stored properly to maintain its effectiveness. It is important to follow the instructions for reconstitution and administration to ensure safety. Patients should inform their healthcare provider about any allergies or medical conditions before using Leucovorin Calcium. Proper disposal of used vials is essential to avoid contamination and ensure safety.

Avoid Interactions

Leucovorin Calcium may interact with certain medications, including folate antagonists like methotrexate. It is important to discuss all current medications with a healthcare provider to avoid potential interactions. Alcohol and other substances may also affect the effectiveness of Leucovorin Calcium. Patients should be aware of these interactions and consult their healthcare provider for personalized advice.

Frequently Asked Questions

Leucovorin Calcium is used to counteract the effects of folate antagonists and to treat folate deficiencies. It is often used in cancer treatments to reduce toxicity from certain chemotherapy drugs.

Leucovorin Calcium 50 mg/5mL is a lyophilized powder that is reconstituted and administered either intramuscularly or intravenously, as directed by a healthcare provider.

Common effects include improved folate levels and reduced toxicity from certain chemotherapy treatments. It helps to restore folate levels in the body.

Yes, it is important to follow the instructions for reconstitution and administration. Patients should inform their healthcare provider about any allergies or medical conditions before using Leucovorin Calcium.

Yes, Leucovorin Calcium may interact with folate antagonists like methotrexate. Patients should discuss all current medications with their healthcare provider to avoid potential interactions.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated: 29 Jul 2026

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