Product image of Levetiracetam Sandoz 100 Mg / 1 Ml, Oral Solution (Levetiracetam) supplied by GNH India

Levetiracetam Sandoz 100 Mg / 1 Ml, Oral Solution

Active Ingredient:
Levetiracetam
Origin:
EU

Levetiracetam Sandoz 100 Mg / 1 Ml, Oral Solution (Levetiracetam)

Levetiracetam, the active ingredient in Levetiracetam Sandoz 100 Mg / 1 mL Oral Solution, is an antiepileptic presented as a 100 mg/mL oral solution for oral use. It is indicated for the treatment of partial‑onset seizures, generalized tonic‑clonic seizures and broader epilepsy management in patients requiring seizure control.

GNH India supplies Levetiracetam Sandoz 100 Mg / 1 mL Oral Solution as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality and regulatory compliance across all markets.

Manufacturer / TM Owner

Sandoz Ltd

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Indications & Clinical Uses

Levetiracetam is an antiepileptic medication used to manage seizure disorders.

  • Partial‑onset seizures: reduces the frequency and severity of focal seizures.
  • Generalized tonic‑clonic seizures: helps prevent convulsive seizure episodes.
  • Epilepsy: provides overall seizure control for patients with diagnosed epilepsy.

How It Works

  • Levetiracetam binds to the synaptic vesicle protein SV2A, modulating neurotransmitter release and stabilizing neuronal firing. This interaction reduces excessive neuronal excitability without directly affecting ion channels or G‑protein pathways, thereby decreasing the likelihood of seizure propagation across the central nervous system. The downstream effect involves alteration of calcium‑dependent exocytosis, contributing to its broad‑spectrum antiepileptic activity.

Side Effects

Levetiracetam may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Dizziness
  • Somnolence
  • Fatigue
  • Irritability

Serious or Rare Side Effects

  • Severe allergic reactions (anaphylaxis)
  • Mood changes including depression or suicidal thoughts
  • Stevens‑Johnson syndrome or other severe skin reactions

Precautions & Warnings

When prescribing Levetiracetam, clinicians should consider several precautionary measures to ensure safe use.

  • Renal impairment: adjust dose based on creatinine clearance.
  • Hepatic impairment: monitor liver function and consider dose modification.
  • Pregnancy: potential risk unknown; discuss benefits and risks with the prescriber.
  • Concomitant CNS depressants: may increase sedation; observe patient response.
  • Mood monitoring: watch for depression or suicidal ideation during therapy.
  • Store at room temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Levetiracetam can interact with other medicines, influencing its effectiveness or safety.

Major Interactions (Avoid)

  • Carbamazepine: may significantly reduce levetiracetam plasma levels.
  • Phenobarbital: can lower levetiracetam concentrations.
  • Phenytoin: may decrease levetiracetam exposure.

Moderate Interactions (Monitor Closely)

  • Alcohol: additive CNS depression may increase drowsiness.
  • Other antiepileptics: potential additive effects on seizure control.
  • Antidepressants: monitor for mood changes or increased side effects.

Frequently Asked Questions

Levetiracetam Sandoz 100 Mg / 1 mL Oral Solution is an antiepileptic liquid formulation indicated for the treatment of partial‑onset seizures, generalized tonic‑clonic seizures, and overall seizure control in patients diagnosed with epilepsy. It is prescribed when a liquid dosage form is preferred, such as for pediatric patients or individuals who have difficulty swallowing tablets.

Levetiracetam exerts its antiepileptic effect by binding to the synaptic vesicle protein SV2A, which plays a key role in neurotransmitter release. This binding modulates vesicle exocytosis, reduces excessive neuronal firing, and stabilizes synaptic transmission, thereby lowering the likelihood of seizure initiation and propagation throughout the brain.

The appropriate dose of Levetiracetam Sandoz Oral Solution is individualized and determined by the prescribing clinician based on the patient’s age, weight, renal function, seizure type, and response to therapy. The prescriber will calculate the exact millilitre volume needed to deliver the required milligram dose.

The safety of levetiracetam during pregnancy and lactation has not been definitively established. It is classified as pregnancy category unknown, so clinicians must weigh potential benefits against possible risks. Women who are pregnant, planning pregnancy, or breastfeeding should discuss treatment options with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide. After the request, the sales team will verify trade or institutional credentials, then provide pricing, availability, shipping details (including any required cold‑chain handling) and import documentation.

Levetiracetam offers a broad spectrum of seizure control with a relatively favorable interaction profile compared with many enzyme‑inducing antiepileptics such as carbamazepine or phenytoin. It does not require routine serum level monitoring and is generally well tolerated, though individual response and side‑effect patterns vary, making it a common alternative to older agents like valproate or phenobarbital.

Levetiracetam Sandoz Oral Solution should be stored at room temperature, below 25 °C, in its original container. Protect the bottle from excessive moisture, direct sunlight, and extreme temperature fluctuations. Do not freeze the solution, and keep the cap tightly closed when not in use.

The solution is taken orally, measured with a calibrated dosing device such as an oral syringe or calibrated cup. It may be administered with or without food, according to the prescriber’s instructions. Patients should follow the exact volume prescribed and avoid altering the concentration by mixing with other liquids unless advised.

Serious risks include severe allergic reactions (e.g., anaphylaxis), significant mood changes such as depression or suicidal thoughts, and rare dermatologic emergencies like Stevens‑Johnson syndrome. Patients should be monitored closely for any new or worsening psychiatric symptoms, skin rash, or signs of hypersensitivity, and seek immediate medical attention if these occur.

Levetiracetam is contraindicated in individuals with known hypersensitivity to levetiracetam or any of the formulation’s excipients. Caution is also advised for patients with severe renal impairment who may require dose adjustment, and for those with a history of serious psychiatric disorders, as they may be at higher risk for mood‑related adverse events.

Reviewed by

Dr. Shweta Ashok More

M.Pharm (Quality Assurance), Ph.D. (Medicinal Chemistry)

Content approved 29 Aug 2026

Last updated:

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