Product image of Lyrica 50 mg/1 (Pregabalin) 50 mg/1 CAPSULE supplied by GNH India

Lyrica 50 mg/1

Active Ingredient:
Pregabalin
Form:
CAPSULE
Brand:
Lyrica
Origin:
USA

Lyrica 50 mg/1 (Pregabalin CAPSULE) 50 mg/1

Pregabalin, the active ingredient in Lyrica 50 mg/1, is an anticonvulsant presented as a 50 mg/capsule for oral use. It is used to manage neuropathic pain, fibromyalgia, and partial onset seizures in adults. GNH India supplies Lyrica 50 mg/1 as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide.

Lyrica 50 mg/1 is a widely recognized medication for its efficacy in treating nerve-related pain and certain types of seizures. It is available in capsule form, making it convenient for oral administration.

Strength

50 mg/1

Pack Size

100 BLISTER PACK in 1 CARTON (0071-1013-41) / 1 CAPSULE in 1 BLISTER PACK

Manufacturer / TM Owner

Parke-Davis Div of Pfizer Inc

1
Pack/s
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Indications & Clinical Uses

Lyrica 50 mg/1 is primarily used to manage neuropathic pain and certain types of seizures. It is effective in treating a range of conditions, including:

  • Neuropathic pain: Reduces pain caused by nerve damage, such as diabetic peripheral neuropathy and postherpetic neuralgia.
  • Fibromyalgia: Alleviates widespread musculoskeletal pain and fatigue associated with this condition.
  • Partial onset seizures: Used as adjunctive therapy to control seizures in adults and children aged 1 month and older.

How It Works

  • Pregabalin works by binding to the α2δ subunit of voltage-gated calcium channels, reducing calcium influx into nerve cells. This action decreases the release of excitatory neurotransmitters, thereby calming overactive nerves and reducing pain signals.

Side Effects

Lyrica 50 mg/1 may cause various side effects, ranging from common to serious or rare.

Common Side Effects

  • Dizziness: A frequent side effect that may affect balance and coordination.
  • Somnolence: Feeling sleepy or drowsy, which can impact daily activities.
  • Peripheral edema: Swelling in the extremities, such as the legs and feet.
  • Dry mouth: A common complaint that can be managed with adequate hydration.
  • Weight gain: Some patients may experience an increase in body weight.

Serious or Rare Side Effects

  • Angioedema: Severe allergic reaction causing swelling of the face, lips, or throat.
  • Suicidal thoughts: Increased risk in patients with a history of depression or suicidal tendencies.
  • Visual disturbances: Blurred vision or other visual changes that may require medical attention.
  • Hypersensitivity reactions: Allergic reactions that can be severe and require immediate medical intervention.

Precautions & Warnings

Lyrica 50 mg/1 should be used with caution and under medical supervision. Important precautions include:

  • Dose adjustment: Required for patients with reduced kidney function to avoid excessive accumulation of the drug.
  • Discontinuation: Should be done gradually to prevent withdrawal symptoms such as seizures, anxiety, and insomnia.
  • Driving and operating machinery: Patients should be cautious as Lyrica may cause dizziness and drowsiness.
  • Alcohol consumption: Should be avoided as it can enhance the sedative effects of the medication.
  • Pregnancy: Should be used with caution, as it is classified as a pregnancy category C drug.
  • Store below 25°C: Keep in the original pack, protect from moisture.

Avoid Interactions

Lyrica 50 mg/1 may interact with other medications, which can affect its efficacy and safety.

Major Interactions (Avoid)

  • Opioids: Concurrent use can enhance central nervous system depression, leading to respiratory depression and sedation.
  • Benzodiazepines: Increased risk of severe sedation and respiratory depression when used together.
  • Alcohol: Can exacerbate the sedative effects of Lyrica, leading to increased drowsiness and dizziness.

Moderate Interactions (Monitor Closely)

  • Antihistamines: May increase the sedative effects of Lyrica, requiring close monitoring.
  • Antidepressants: Some antidepressants can enhance the side effects of Lyrica, such as dizziness and drowsiness.
  • Antipsychotics: May increase the risk of sedation and other central nervous system side effects.

Frequently Asked Questions

Lyrica 50 mg/1 is used to manage neuropathic pain, fibromyalgia, and partial onset seizures. It is effective in reducing pain caused by nerve damage, such as diabetic peripheral neuropathy and postherpetic neuralgia, as well as alleviating widespread musculoskeletal pain and fatigue associated with fibromyalgia. It is also used as adjunctive therapy to control seizures in adults and children aged 1 month and older.

Pregabalin works by binding to the α2δ subunit of voltage-gated calcium channels, reducing calcium influx into nerve cells. This action decreases the release of excitatory neurotransmitters, thereby calming overactive nerves and reducing pain signals. This mechanism makes it effective in managing neuropathic pain and certain types of seizures.

The usual dose of Lyrica 50 mg/1 is determined by a healthcare professional based on the patient's condition and response to treatment. It is important to follow the prescribed dosage and not to adjust it without medical advice. The dosage may vary depending on the specific condition being treated and the patient's individual needs.

Lyrica 50 mg/1 is classified as a pregnancy category C drug, meaning it should be used with caution during pregnancy. It is important to discuss the potential risks and benefits with a healthcare professional. The safety of Lyrica during breastfeeding has not been established, and it is recommended to consult a healthcare provider before using it while breastfeeding.

To order Lyrica 50 mg/1 from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets. The team will ask you to confirm your trade or institutional credentials and will reply with pricing, availability, shipping, and the necessary import paperwork.

Lyrica 50 mg/1 is one of the most effective medications for managing neuropathic pain. It is often compared to other anticonvulsants and analgesics. Its unique mechanism of action makes it a preferred choice for conditions like diabetic peripheral neuropathy and postherpetic neuralgia. However, the choice of medication depends on individual patient needs and response to treatment.

Lyrica 50 mg/1 should be stored below 25°C, in the original pack, and protected from moisture. It is important to keep the medication out of reach of children and to follow the storage instructions provided on the packaging. Proper storage ensures the effectiveness and safety of the medication.

Lyrica 50 mg/1 is administered orally, typically in capsule form. It can be taken with or without food, as food does not significantly affect its absorption. The capsules should be swallowed whole with a glass of water. The dosage and frequency of administration are determined by a healthcare professional based on the patient's condition and response to treatment.

The most serious risks associated with Lyrica 50 mg/1 include angioedema, suicidal thoughts, and visual disturbances. Patients should be monitored for signs of severe allergic reactions, changes in mood or behavior, and any visual changes. Immediate medical attention should be sought if any of these serious side effects occur.

Lyrica 50 mg/1 should not be used by individuals who are allergic to Pregabalin or any of its ingredients. It should be used with caution in patients with a history of heart disease, kidney disease, or a tendency for suicidal thoughts. Pregnant women and breastfeeding mothers should consult a healthcare professional before using Lyrica 50 mg/1.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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