Product image of Maexeni 20 (Ethinylestradiol, Levonorgestrel) supplied by GNH India

Maexeni 20

Active Ingredient:
Ethinylestradiol, Levonorgestrel
Origin:
EU

Maexeni 20 (Ethinylestradiol, Levonorgestrel)

Ethinylestradiol and Levonorgestrel, the active ingredients in Maexeni 20, are a combined oral contraceptive presented as a tablet for oral use. They prevent pregnancy in women of reproductive age.

GNH India supplies Maexeni 20 as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Hormosan Pharma Gmbh

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Indications & Clinical Uses

  • Maexeni 20, a combined oral contraceptive, is used within the hormonal contraception pathway to prevent pregnancy.
  • Contraception:
  • 1. Provides effective prevention of ovulation and pregnancy.
  • 2. Menstrual cycle regulation: helps achieve more regular menstrual bleeding patterns.
  • 3. Treatment of dysmenorrhea: can reduce painful menstrual cramps.

How It Works

  • Ethinylestradiol and levonorgestrel act by suppressing the hypothalamic‑pituitary‑ovarian axis, inhibiting the mid‑cycle surge of luteinising hormone and preventing ovulation. The estrogen component stabilises the endometrial lining, while the progestin thickens cervical mucus and alters the endometrium, creating conditions unfavorable for fertilisation and implantation.

Side Effects

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Headache: tension‑type or migraine‑like pain.
  • Breast tenderness: temporary swelling or discomfort.
  • Spotting between periods: irregular light bleeding.

Serious or Rare Side Effects

  • Deep vein thrombosis: blood clot formation in deep veins.
  • Pulmonary embolism: clot migration to lung vessels.
  • Severe allergic reaction: anaphylaxis with rash, swelling, or breathing difficulty.

Precautions & Warnings

Before starting Maexeni 20, consider the following precautions:

  • Smoking: avoid use if over 35 years and a smoker due to increased thrombotic risk.
  • Cardiovascular disease: assess risk of heart attack or stroke before prescribing.
  • History of thromboembolism: contraindicated in patients with prior clotting events.
  • Liver disease: monitor hepatic function as metabolism occurs in the liver.
  • Migraine with aura: avoid as it may elevate stroke risk.
  • Store at ambient temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Maexeni 20 may interact with several medicines. Review patient medication lists carefully.

Major Interactions (Avoid)

  • Rifampin: strong CYP3A4 inducer that reduces contraceptive efficacy.
  • Phenytoin: enzyme inducer leading to decreased hormone levels.
  • Carbamazepine: lowers plasma concentrations of both hormones.

Moderate Interactions (Monitor Closely)

  • St. John’s wort: herbal inducer that may diminish effectiveness.
  • Ketoconazole: antifungal that can increase hormone levels.
  • Ritonavir: antiretroviral that may alter hormone metabolism.
  • Ciprofloxacin: fluoroquinolone antibiotic with potential modest effect.

Frequently Asked Questions

Maexeni 20 is a combined oral contraceptive tablet containing ethinylestradiol and levonorgestrel. It is prescribed to prevent pregnancy in women of reproductive age by inhibiting ovulation and creating an environment that is unfavorable for fertilisation and implantation.

Ethinylestradiol, the estrogen component, stabilises the endometrial lining and works with levonorgestrel to suppress the luteinising hormone surge, thereby preventing the release of an egg from the ovary.

The dosing regimen for Maexeni 20 is determined by the prescribing clinician. Typically, it is taken once daily as directed, but the exact schedule and duration should follow the healthcare provider’s instructions.

Maexeni 20 is intended for use only when pregnancy is not desired. It should not be started during pregnancy, and if pregnancy occurs, the product must be discontinued. Safety during breastfeeding is evaluated case‑by‑case; clinicians usually advise caution and may recommend alternative contraception.

To order Maexeni 20, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Maexeni 20 contains a low‑dose ethinylestradiol (20 µg) combined with levonorgestrel, offering effective contraception with a potentially lower risk of estrogen‑related side effects compared with higher‑dose formulations. Its efficacy and safety profile are comparable to other approved combined pills that use similar hormone ratios.

Store Maexeni 20 tablets at ambient temperature, below 25 °C. Keep them in the original packaging, protect from moisture and direct sunlight, and ensure the container is tightly closed to maintain tablet integrity.

Maexeni 20 is taken orally, usually once daily at the same time each day. Patients should swallow the tablet whole with water and follow the specific cycle regimen prescribed by their healthcare professional.

Serious risks include thromboembolic events such as deep‑vein thrombosis, pulmonary embolism, stroke, and myocardial infarction. Rare allergic reactions like anaphylaxis may also occur. Patients should seek immediate medical attention if they experience symptoms such as severe leg pain, shortness of breath, chest pain, or sudden swelling.

Maexeni 20 is contraindicated in women who are pregnant, have a history of thromboembolic disorders, uncontrolled hypertension, certain cardiovascular diseases, severe liver disease, or known hypersensitivity to any component of the tablet. It should also be avoided by smokers over 35 years of age.

Medically reviewed by

Dr. Shweta Ashok More

M.Pharm (Quality Assurance), Ph.D. (Medicinal Chemistry), GNH India Pharmaceuticals Limited · Reviewed 31 Aug 2026

Published by GNH India Pharmaceuticals Limited · Last updated

References

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