Marcaine with Epinephrine 5 mg/mL (Bupivacaine Hydrochloride and Epinephrine Bitartrate INJECTION, SOLUTION) 5 mg/mL

Marcaine with Epinephrine 5 mg/mL is a local anesthetic injection used for pain relief. It combines bupivacaine hydrochloride and epinephrine bitartrate for effective numbing. Ideal for epidural, intracaudal, and perineural applications.

Strength

5 mg/mL

Pack Size

10 VIAL, SINGLE-DOSE in 1 CARTON (0409-1749-29) / 30 mL in 1 VIAL, SINGLE-DOSE (0409-1749-71)

Manufacturer / TM Owner

Hospira, Inc.

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Indications & Clinical Uses

Marcaine with Epinephrine 5 mg/mL is primarily used for local anesthesia, providing pain relief during medical procedures. It is often administered for epidural, intracaudal, and perineural blocks. This combination of bupivacaine and epinephrine helps to prolong the numbing effect, making it suitable for various surgical and dental applications. Patients may wonder what Marcaine with Epinephrine is used for, and it is typically utilized in settings where prolonged pain relief is required.

Side Effects

Common effects of Marcaine with Epinephrine 5 mg/mL may include temporary numbness and reduced pain sensation in the treated area. Some individuals might experience mild swelling, redness, or itching at the injection site. These effects are generally short-lived and subside as the medication wears off. It is important to monitor for any unusual reactions and consult a healthcare provider if concerns arise.

Precautions & Warnings

Marcaine with Epinephrine 5 mg/mL should be handled with care to avoid contamination. It is essential to follow proper injection techniques and dispose of used vials safely. Patients with a known allergy to local anesthetics or epinephrine should avoid this medication. Always store the vials as per the manufacturer's guidelines to maintain efficacy.

Avoid Interactions

Marcaine with Epinephrine 5 mg/mL may interact with other medications, particularly those that affect blood pressure or heart rate. It is advisable to inform healthcare providers about all current medications before administration. Avoid combining with other anesthetics unless directed by a professional. Alcohol and certain supplements may also influence the effects of this medication.

Frequently Asked Questions

Marcaine with Epinephrine 5 mg/mL is used for local anesthesia, providing pain relief during medical procedures such as epidural, intracaudal, and perineural blocks.

Marcaine with Epinephrine 5 mg/mL should be stored according to the manufacturer's guidelines to maintain its effectiveness.

Common effects include temporary numbness and reduced pain sensation in the treated area, along with possible mild swelling or itching at the injection site.

It may interact with other medications, particularly those affecting blood pressure or heart rate. Consult a healthcare provider before combining with other drugs.

Patients with allergies to local anesthetics or epinephrine should avoid this medication. Always consult a healthcare provider to ensure safety.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated: 29 Jul 2026

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