Marcaine with Epinephrine 5 mg/mL (Bupivacaine Hydrochloride and Epinephrine INJECTION, SOLUTION) 5 mg/mL

Marcaine with Epinephrine 5 mg/mL is a local anesthetic injection solution containing bupivacaine hydrochloride and epinephrine. It is commonly used for pain relief in various medical procedures. This product is manufactured by Hospira, Inc. in the USA.

Strength

5 mg/mL

Pack Size

10 VIAL, SINGLE-DOSE in 1 CARTON (0409-4208-10) / 30 mL in 1 VIAL, SINGLE-DOSE (0409-4208-01)

Manufacturer / TM Owner

Hospira, Inc.

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Indications & Clinical Uses

Marcaine with Epinephrine 5 mg/mL is primarily used for local anesthesia, providing pain relief during surgical procedures, dental work, or other medical treatments. It is often administered epidurally, intracaudally, or perineurally to numb specific areas of the body. This medication is designed to block nerve signals, thereby reducing pain sensations in the targeted region.

Side Effects

When administered, Marcaine with Epinephrine 5 mg/mL typically provides localized numbing effects, which can last for several hours. Users may experience a temporary loss of sensation in the treated area. The addition of epinephrine helps to prolong the anesthetic effect and reduce bleeding at the injection site.

Precautions & Warnings

Marcaine with Epinephrine 5 mg/mL should be handled with care, ensuring proper sterile techniques are followed during administration. It is important to inform healthcare providers about any known allergies or sensitivities to local anesthetics. This medication should be used under the supervision of a qualified healthcare professional.

Avoid Interactions

Marcaine with Epinephrine 5 mg/mL may interact with certain medications, including other local anesthetics, blood thinners, and some cardiovascular drugs. It is advisable to discuss all current medications with a healthcare provider before use. Additionally, the use of this medication with alcohol or other depressants should be avoided.

Frequently Asked Questions

Marcaine with Epinephrine 5 mg/mL is used for local anesthesia to provide pain relief during various medical procedures.

This medication is typically administered epidurally, intracaudally, or perineurally by a healthcare professional.

Common effects include localized numbing and a temporary loss of sensation in the treated area.

Yes, it is important to inform healthcare providers about any allergies or sensitivities to local anesthetics and to use this medication under professional supervision.

Yes, it may interact with other local anesthetics, blood thinners, and some cardiovascular drugs. Always consult a healthcare provider.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated: 29 Jul 2026

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