Marcaine with Epinephrine 5 mg/mL (Bupivacaine Hydrochloride and Epinephrine INJECTION, SOLUTION) 5 mg/mL

Marcaine with Epinephrine 5 mg/mL is a local anesthetic injection solution used for pain relief. It combines bupivacaine hydrochloride and epinephrine for effective numbing during medical procedures.

Strength

5 mg/mL

Pack Size

10 VIAL, SINGLE-DOSE in 1 CARTON (0409-8126-10) / 10 mL in 1 VIAL, SINGLE-DOSE (0409-8126-01)

Manufacturer / TM Owner

Hospira, Inc.

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Indications & Clinical Uses

Marcaine with Epinephrine 5 mg/mL is primarily used for local anesthesia. It is commonly administered for pain relief during surgical procedures, dental work, or other medical interventions. The combination of bupivacaine and epinephrine helps to prolong the numbing effect and reduce bleeding at the injection site. This solution is often used in epidural, intracaudal, and perineural applications.

Side Effects

When administered, Marcaine with Epinephrine 5 mg/mL typically provides localized numbness and pain relief. Patients may experience a temporary loss of sensation in the treated area. The effects usually last for several hours, depending on the specific application and individual response.

Precautions & Warnings

Marcaine with Epinephrine 5 mg/mL should be handled with care. It is important to follow proper sterile techniques when preparing and administering the injection. Patients with a known allergy to local anesthetics or epinephrine should avoid this medication. Always consult a healthcare provider before use.

Avoid Interactions

Marcaine with Epinephrine 5 mg/mL may interact with certain medications, including other local anesthetics, beta-blockers, and monoamine oxidase inhibitors. It is also important to avoid alcohol consumption while using this medication, as it can enhance the sedative effects. Always inform your healthcare provider about all medications you are taking.

Frequently Asked Questions

Marcaine with Epinephrine 5 mg/mL is used for local anesthesia during medical procedures to provide pain relief and reduce bleeding.

The numbing effect typically lasts for several hours, depending on the specific application and individual response.

Yes, Marcaine with Epinephrine 5 mg/mL is commonly used for dental procedures to provide local anesthesia and pain relief.

Common side effects may include temporary numbness, tingling, or swelling at the injection site.

Patients with a known allergy to local anesthetics or epinephrine should avoid this medication. Always consult a healthcare provider before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated: 29 Jul 2026

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