Product image of Meralys 1 Mg/Ml (Xylometazoline Hydrochloride) supplied by GNH India

Meralys 1 Mg/Ml

Active Ingredient:
Xylometazoline Hydrochloride
Origin:
EU

Meralys 1 Mg/Ml (Xylometazoline Hydrochloride)

Xylometazoline Hydrochloride, the active ingredient in Meralys 1 Mg/mL, is an imidazoline derivative presented as a 1 mg/mL nasal solution for nasal use. It relieves nasal congestion associated with the common cold, sinusitis and allergic rhinitis in adults and children.

GNH India supplies Meralys 1 Mg/mL as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, clinics and other healthcare facilities worldwide, with a focus on quality and regulatory compliance. The product meets EU pharmacopeial standards and is manufactured under GMP conditions.

Manufacturer / TM Owner

Jadran-Galenski Laboratorij D.D.

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Indications & Clinical Uses

Xylometazoline Hydrochloride is a topical nasal decongestant that reduces swelling of the nasal mucosa, improving airflow.

  • Common cold: alleviates nasal congestion by constricting dilated blood vessels in the nasal mucosa, providing rapid relief of a blocked nose.
  • Sinusitis: decreases mucosal edema in the sinus passages, helping to restore normal breathing and drainage.
  • Allergic rhinitis: reduces congestion caused by allergic inflammation, improving nasal patency during exposure to allergens.

How It Works

  • Xylometazoline Hydrochloride acts as a topical alpha‑adrenergic agonist, binding to α‑adrenergic receptors on the smooth muscle of nasal mucosal blood vessels. This stimulation induces vasoconstriction, which reduces blood flow, diminishes edema, and opens the nasal airway, thereby relieving congestion.

Side Effects

Xylometazoline Hydrochloride may cause local and systemic adverse reactions, most of which are mild and transient.

Common Side Effects

  • Nasal irritation or burning sensation
  • Dryness of nasal mucosa
  • Sneezing
  • Headache
  • Epistaxis (nosebleeds)

Serious or Rare Side Effects

  • Severe hypertension
  • Tachycardia or arrhythmia
  • Allergic reactions such as rash, itching or swelling
  • Rebound nasal congestion (rhinitis medicamentosa) with prolonged use
  • Nasal ulceration

Precautions & Warnings

When using Meralys, consider the following precautions to ensure safe and effective treatment.

  • Use in children under 2 years: not recommended
  • Pregnancy: consult a healthcare professional before use
  • Existing hypertension or cardiovascular disease: use with caution
  • Concurrent use of monoamine oxidase inhibitors (MAOIs): avoid due to additive sympathomimetic effects
  • Prolonged use beyond 3 days: risk of rebound congestion; limit duration
  • Store at room temperature: keep in original container, protect from light and moisture

Avoid Interactions

Xylometazoline Hydrochloride can interact with other medications, requiring attention to avoid adverse effects.

Major Interactions (Avoid)

  • Oral decongestants such as pseudoephedrine: additive sympathomimetic activity may raise blood pressure
  • Monoamine oxidase inhibitors (MAOIs): risk of hypertensive crisis
  • Tricyclic antidepressants: may enhance cardiovascular stimulation

Moderate Interactions (Monitor Closely)

  • Beta‑blockers: may mask tachycardia induced by the nasal spray
  • Antihypertensive agents: possible reduction in blood pressure control
  • Other intranasal medications: increased local irritation when used together

Frequently Asked Questions

Meralys 1 Mg/mL contains Xylometazoline Hydrochloride and is indicated for the temporary relief of nasal congestion associated with the common cold, sinusitis and allergic rhinitis. It works by narrowing the blood vessels in the nasal passages, helping to open the airway.

Xylometazoline Hydrochloride is a topical alpha‑adrenergic agonist. By stimulating α‑adrenergic receptors on nasal blood vessels, it causes vasoconstriction, which reduces swelling of the nasal mucosa and improves airflow, thereby relieving congestion.

The appropriate dose of Meralys is determined by a qualified healthcare professional. Typically, a few drops are administered into each nostril as directed, and the frequency should not exceed the label‑recommended maximum to avoid rebound congestion.

Safety data for Xylometazoline Hydrochloride in pregnancy and lactation are limited. Women who are pregnant, planning pregnancy, or breastfeeding should discuss use with their physician, who can weigh potential benefits against any possible risks.

To order Meralys, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Meralys contains Xylometazoline, an imidazoline‑type decongestant, which provides rapid onset of action similar to phenylephrine‑based sprays. Compared with oxymetazoline, it has a comparable efficacy profile but may differ slightly in duration of effect and tolerability, making choice dependent on individual response and physician preference.

Store Meralys at room temperature, below 25 °C, in its original container. Protect the bottle from direct sunlight, moisture and extreme temperatures. Keep the cap tightly closed when not in use to maintain sterility.

Meralys is applied as a nasal solution. The user tilts the head slightly forward, inserts the tip into a nostril, and delivers the prescribed number of drops. The same procedure is repeated for the other nostril if required.

Serious risks include severe hypertension, tachycardia or arrhythmias, allergic reactions, and rebound nasal congestion (rhinitis medicamentosa) if used for more than three consecutive days. Patients experiencing these symptoms should discontinue use and seek medical attention promptly.

Meralys should be avoided in children under two years of age, in individuals with known hypersensitivity to Xylometazoline or any formulation component, and in patients taking monoamine oxidase inhibitors. Those with uncontrolled hypertension or severe cardiovascular disease should consult a physician before use.

Medically reviewed by

Dr. Shweta Ashok More

M.Pharm (Quality Assurance), Ph.D. (Medicinal Chemistry), GNH India Pharmaceuticals Limited · Reviewed 8 Sep 2026

Published by GNH India Pharmaceuticals Limited · Last updated

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