Product image of Meralys (Xylometazoline Hydrochloride) supplied by GNH India

Meralys

Active Ingredient:
Xylometazoline Hydrochloride
Origin:
EU

Meralys (Xylometazoline Hydrochloride)

Xylometazoline Hydrochloride, the active ingredient in Meralys, is an alpha-adrenergic agonist presented as a nasal spray for nasal use. It relieves nasal congestion associated with the common cold, sinusitis, and allergic rhinitis, providing rapid improvement in breathing.\n\nGNH India supplies Meralys as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Jadran-Galenski Laboratorij D.D.

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Indications & Clinical Uses

  • Xylometazoline Hydrochloride is a nasal decongestant that reduces swelling of nasal mucosa in upper‑respiratory conditions.\n\n- Common cold: alleviates nasal congestion and improves airflow.\n- Sinusitis: reduces mucosal swelling to ease sinus drainage.\n- Allergic rhinitis: diminishes nasal blockage caused by allergic inflammation.

How It Works

  • Xylometazoline Hydrochloride acts as a selective alpha‑adrenergic receptor agonist on the blood vessels of the nasal mucosa. By stimulating these receptors, it induces vasoconstriction, which decreases blood flow and edema in the nasal passages, leading to reduced congestion and improved airway patency.

Side Effects

  • Xylometazoline Hydrochloride may cause local and systemic adverse reactions, most of which are mild and reversible.\n\nCommon Side Effects:\n- Nasal burning or stinging: mild irritation at the application site.\n- Sneezing: transient reflex response.\n- Dry nasal mucosa: dryness or crusting.\n- Headache: mild headache.\n\nSerious or Rare Side Effects:\n- Nasal septum perforation: rare tissue damage with prolonged use.\n- Hypertension: elevated blood pressure in susceptible individuals.\n- Rebound congestion: worsening nasal blockage after extended use.\n- Allergic reaction: rash, itching, or swelling.

Precautions & Warnings

  • When using Meralys, consider the following safety measures.\n\n- Duration of use: limit to 3‑5 days to avoid rebound congestion.\n- Age restrictions: not recommended for children under 6 years without medical advice.\n- Pregnancy and lactation: consult a healthcare professional before use.\n- Existing cardiovascular disease: use with caution due to possible systemic vasoconstriction.\n- Concurrent nasal sprays: avoid using other decongestant sprays simultaneously.\n- Store at room temperature: keep in original container, protect from moisture and direct sunlight.

Avoid Interactions

  • Xylometazoline Hydrochloride can interact with certain medications, affecting its safety profile.\n\nMajor Interactions (Avoid):\n- Monoamine oxidase inhibitors (MAOIs): risk of excessive vasoconstriction.\n- Sympathomimetic drugs: additive hypertensive effect.\n\nModerate Interactions (Monitor Closely):\n- Antihypertensive agents: may reduce blood pressure control.\n- Nasal corticosteroids: monitor for increased local irritation.\n- Other nasal decongestants: risk of cumulative vasoconstriction.

Frequently Asked Questions

Meralys is an OTC nasal spray containing Xylometazoline Hydrochloride. It is used to relieve nasal congestion caused by the common cold, sinusitis, and allergic rhinitis by narrowing the blood vessels in the nasal lining, which reduces swelling and improves airflow.

Xylometazoline Hydrochloride is a selective alpha‑adrenergic agonist. When applied to the nasal mucosa, it stimulates alpha‑adrenergic receptors on blood vessels, causing vasoconstriction. This reduces blood flow and edema in the nasal passages, leading to decreased congestion and easier breathing.

The dosage of Meralys is determined by the prescribing healthcare professional. Typically, a few sprays per nostril are administered, but the exact number of sprays, frequency, and duration should follow the prescriber’s instructions and the product label.

Safety data for Xylometazoline Hydrochloride in pregnancy or lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should consult their physician before using Meralys to weigh potential benefits against any unknown risks.

To order Meralys, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Meralys contains Xylometazoline, a selective alpha‑adrenergic agonist, which provides rapid decongestion similar to other OTC agents like oxymetazoline. Compared with older compounds, Xylometazoline often has a slightly longer duration of action and a comparable safety profile when used as directed.

Store Meralys at room temperature, away from direct sunlight and moisture. Keep the spray in its original packaging to protect the nozzle and maintain sterility. Do not freeze the product, and ensure the cap is tightly closed when not in use.

Meralys is administered as a nasal spray. The user tilts the head slightly forward, inserts the nozzle into one nostril, and sprays the prescribed number of sprays while breathing in gently. The process is repeated in the other nostril if required, following the prescriber’s guidance.

Serious risks, though rare, include nasal septum perforation, significant hypertension, and rebound congestion after prolonged use. An allergic reaction such as rash, itching, or swelling may also occur. Users should discontinue the spray and seek medical attention if any of these events arise.

Meralys should be avoided by individuals with known hypersensitivity to Xylometazoline or any component of the formulation. It is also contraindicated in patients using MAO inhibitors, those with severe hypertension, or anyone advised by a healthcare professional to refrain from nasal decongestants.

Medically reviewed by

Dr. Shweta Ashok More

M.Pharm (Quality Assurance), Ph.D. (Medicinal Chemistry), GNH India Pharmaceuticals Limited · Reviewed 8 Sep 2026

Published by GNH India Pharmaceuticals Limited · Last updated

References

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