Product image of Meriofert Kit (Follicle-Stimulating Hormone, Luteinising Hormone) supplied by GNH India

Meriofert Kit

Active Ingredient:
Follicle-Stimulating Hormone, Luteinising Hormone
Origin:
EU

Meriofert Kit (Follicle-Stimulating Hormone, Luteinising Hormone)

Follicle-Stimulating Hormone; Luteinising Hormone, the active ingredient in Meriofert Kit, is a gonadotropin presented as a sterile injectable solution for subcutaneous use. It is employed in reproductive medicine to stimulate follicular development, ovulation and luteinisation in women with anovulatory infertility or hypogonadotropic hypogonadism.

GNH India supplies Meriofert Kit as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, fertility clinics and pharmacies worldwide. The company adheres to stringent quality standards and provides cold‑chain logistics where required.

Manufacturer / TM Owner

Ibsa Pharma Kft

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Indications & Clinical Uses

  • Meriofert Kit, containing FSH and LH, acts on the hypothalamic‑pituitary‑gonadal axis to support reproductive function.
  • Infertility due to anovulation: promotes follicular growth and ovulation in women who do not ovulate spontaneously.
  • Assisted reproductive technology (ART) protocols: provides controlled ovarian stimulation for IVF and ICSI cycles.
  • Hypogonadotropic hypogonadism: replaces deficient gonadotropins to restore normal ovarian activity.

How It Works

  • Follicle‑Stimulating Hormone and Luteinising Hormone bind to their respective receptors on ovarian granulosa and theca cells. Activation of FSH receptors stimulates follicle recruitment and estradiol production, while LH receptor activation triggers final maturation, ovulation and luteinisation. The combined action enhances follicular development and prepares the ovary for successful conception.

Side Effects

Adverse reactions may occur with any gonadotropin therapy.

Common Side Effects

  • Injection site pain or erythema
  • Mild abdominal discomfort or bloating
  • Nausea or mild vomiting
  • Headache
  • Transient ovarian hyperstimulation (mild)
  • Fatigue

Serious or Rare Side Effects

  • Severe ovarian hyperstimulation syndrome
  • Thromboembolic events
  • Allergic reaction or anaphylaxis
  • Multiple pregnancy
  • Ectopic pregnancy
  • Vision disturbances or retinal detachment

Precautions & Warnings

Use of Meriofert Kit requires careful clinical monitoring.

  • Assess ovarian response before initiating therapy: baseline ultrasound and hormone levels.
  • Monitor estradiol and follicle size during stimulation.
  • Avoid in patients with known hypersensitivity to gonadotropins.
  • Use caution in women with ovarian cysts, endometriosis or uncontrolled thyroid disease.
  • Do not exceed the recommended number of stimulation cycles per year.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Gonadotropin therapy can be affected by other hormonal agents.

Major Interactions (Avoid)

  • GnRH agonists: may blunt response if timing is incorrect.
  • Oral contraceptives: suppress endogenous gonadotropins, reducing efficacy.
  • High‑dose estrogen therapy: antagonises FSH/LH action.

Moderate Interactions (Monitor Closely)

  • Anticoagulants: increased risk of ovarian bleeding.
  • Thyroid hormone replacement: may alter ovarian response.
  • Corticosteroids: can affect hormone metabolism and response.

Frequently Asked Questions

Meriofert Kit is used in reproductive medicine to stimulate follicular development, induce ovulation and support luteinisation in women with anovulatory infertility, during assisted reproductive technology cycles, and in patients with hypogonadotropic hypogonadism who lack adequate endogenous gonadotropins.

FSH binds to receptors on ovarian granulosa cells, promoting follicle growth and estradiol synthesis, while LH binds to receptors on theca and luteal cells, triggering final follicle maturation, ovulation and luteinisation. Together they coordinate the hormonal cascade required for successful oocyte release and preparation of the endometrium.

The dose of Meriofert Kit is individualized by the prescribing clinician based on the patient’s age, ovarian reserve, treatment protocol and response to monitoring. The prescriber determines the exact amount, frequency and duration of subcutaneous injections for each treatment cycle.

Meriofert Kit is intended for use before conception to facilitate ovulation. Its safety in established pregnancy or while breastfeeding has not been established, and it should not be used during those periods unless specifically directed by a qualified specialist.

To order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain where required) and necessary import documentation.

Meriofert Kit combines both FSH and LH in a single injectable formulation, offering a convenient alternative to using separate FSH‑only and LH‑only preparations. This dual‑action product can simplify dosing schedules and may improve synchronization of follicular development compared with single‑component gonadotropins.

Meriofert Kit must be stored refrigerated at 2‑8 °C, protected from light, and must not be frozen or shaken. Before use, allow the vial to reach room temperature for a few minutes, and inspect for particulate matter or discoloration. Follow aseptic technique for subcutaneous injection.

Meriofert Kit is supplied as a sterile solution for subcutaneous injection. The prescriber will instruct the patient on the injection site (typically the abdomen or thigh), rotation of sites, and the exact volume to administer using a sterile needle and syringe. Injections are usually given once daily or as per the specific stimulation protocol.

The most serious risks include severe ovarian hyperstimulation syndrome, which can cause fluid shifts, thromboembolic events, and in rare cases, ovarian torsion. Allergic reactions, including anaphylaxis, and multiple pregnancy are also significant concerns that require prompt medical attention.

Meriofert Kit should not be used in individuals with known hypersensitivity to any gonadotropin component, in patients with active ovarian cysts, uncontrolled thyroid disease, or in women who are already pregnant. It is also contraindicated in those with severe ovarian hyperstimulation syndrome from a previous cycle.

Medically reviewed by

Dr. Shweta Ashok More

M.Pharm (Quality Assurance), Ph.D. (Medicinal Chemistry), GNH India Pharmaceuticals Limited · Reviewed 8 Sep 2026

Published by GNH India Pharmaceuticals Limited · Last updated

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