Methotrexate 25 mg/mL (Methotrexate INJECTION) 25 mg/mL

Methotrexate 25 mg/mL is a versatile injectable medication used for various conditions. This prescription drug is available in 10 mL vials and is manufactured by Accord Healthcare, Inc. in the USA.

Strength

25 mg/mL

Pack Size

1 VIAL in 1 CARTON (16729-277-03) / 10 mL in 1 VIAL

Manufacturer / TM Owner

Accord Healthcare, Inc.

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Pack/s

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Indications & Clinical Uses

Methotrexate is commonly used for its immunosuppressive and anti-inflammatory properties. It is often prescribed for conditions like rheumatoid arthritis, psoriasis, and certain types of cancer. The medication works by interfering with the growth of certain cells in the body. Methotrexate 25 mg/mL injection is administered via intra-arterial, intramuscular, intrathecal, or intravenous routes, depending on the specific condition being treated.

Side Effects

Methotrexate can cause various side effects, which may include nausea, fatigue, and mouth sores. Some individuals may experience more severe reactions, such as liver toxicity or lung problems. It is important to monitor for any adverse effects and consult a healthcare provider if they occur.

Precautions & Warnings

Methotrexate should be handled with care and stored properly to maintain its effectiveness. It is crucial to follow the prescribed dosage and administration instructions. Pregnant women or those planning to become pregnant should avoid using Methotrexate due to potential risks to the fetus. Always inform your healthcare provider about any other medications you are taking to avoid potential interactions.

Avoid Interactions

Methotrexate can interact with various medications, including nonsteroidal anti-inflammatory drugs (NSAIDs), antibiotics, and certain vaccines. Alcohol consumption should be avoided as it can increase the risk of side effects. It is also important to be cautious when taking Methotrexate with other immunosuppressive drugs, as this can enhance the risk of infections.

Frequently Asked Questions

Methotrexate is used for its immunosuppressive and anti-inflammatory properties, often prescribed for conditions like rheumatoid arthritis, psoriasis, and certain cancers.

Methotrexate 25 mg/mL can be administered via intra-arterial, intramuscular, intrathecal, or intravenous routes, depending on the specific condition being treated.

Common side effects of Methotrexate include nausea, fatigue, and mouth sores. More severe reactions can include liver toxicity or lung problems.

Methotrexate should be avoided during pregnancy due to potential risks to the fetus. Consult a healthcare provider for personalized advice.

Precautions include following the prescribed dosage, avoiding alcohol, and informing your healthcare provider about other medications you are taking.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated: 29 Jul 2026

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