Product image of MOUNJARO 10 mg/.5mL (Tirzepatide) 10 mg/.5mL INJECTION, SOLUTION supplied by GNH India

MOUNJARO 10 mg/.5mL

Active Ingredient:
Tirzepatide
Form:
INJECTION, SOLUTION
Brand:
MOUNJARO
Origin:
USA

MOUNJARO 10 mg/.5mL (Tirzepatide INJECTION, SOLUTION) 10 mg/.5mL

Tirzepatide, the active ingredient in MOUNJARO 10 mg/0.5mL, is a glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist presented as a 10 mg/0.5mL injection, solution for subcutaneous use. It is used as an adjunct to diet and exercise to improve glycemic control in adults and pediatric patients 10 years of age and older with type 2 diabetes mellitus.

GNH India supplies MOUNJARO 10 mg/0.5mL as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide.

Strength

10 mg/.5mL

Pack Size

4 SYRINGE in 1 CARTON (0002-1471-80) / .5 mL in 1 SYRINGE (0002-1471-01)

Manufacturer / TM Owner

Eli Lilly and Company

1
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Indications & Clinical Uses

MOUNJARO 10 mg/0.5mL is indicated for the management of type 2 diabetes mellitus through its action on GIP and GLP-1 pathways.

  • Type 2 Diabetes Mellitus: Improves glycemic control in adults and pediatric patients 10 years of age and older.
  • Cardiovascular Risk Reduction: Reduces the risk of major adverse cardiovascular events in adults with type 2 diabetes mellitus who are at high risk for these events.

How It Works

  • Tirzepatide is a GIP receptor and GLP-1 receptor agonist. It enhances first- and second-phase insulin secretion and reduces glucagon levels in a glucose-dependent manner. By activating these receptors, tirzepatide lowers fasting and postprandial glucose concentrations, decreases food intake, and reduces body weight in patients with type 2 diabetes mellitus.

Side Effects

MOUNJARO 10 mg/0.5mL may cause various side effects, ranging from common to serious.

Common Side Effects

  • Nausea
  • Diarrhea
  • Decreased appetite
  • Vomiting
  • Constipation
  • Indigestion
  • Abdominal pain

Serious or Rare Side Effects

  • Acute pancreatitis
  • Hypoglycemia when used with insulin secretagogues or insulin
  • Hypersensitivity reactions, including anaphylaxis and angioedema
  • Acute kidney injury due to volume depletion
  • Severe gastrointestinal adverse reactions
  • Diabetic retinopathy complications in patients with a history of diabetic retinopathy

Precautions & Warnings

MOUNJARO 10 mg/0.5mL should be used with caution and certain precautions should be observed.

  • Acute Pancreatitis: Discontinue if suspected.
  • Hypoglycemia: Monitor closely when used with insulin secretagogues or insulin.
  • Hypersensitivity Reactions: Discontinue if suspected and seek medical advice.
  • Acute Kidney Injury: Monitor renal function in patients reporting adverse reactions that could lead to volume depletion.
  • Severe Gastrointestinal Adverse Reactions: Not recommended in patients with severe gastroparesis.
  • Store at 2-8°C: Keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

MOUNJARO 10 mg/0.5mL may interact with other medications, requiring careful monitoring or avoidance.

Major Interactions (Avoid)

  • Oral Contraceptives: Advise females to switch to a non-oral contraceptive method or add a barrier method of contraception for 4 weeks after initiation and for 4 weeks after each dose escalation.

Moderate Interactions (Monitor Closely)

  • Oral Medications: MOUNJARO delays gastric emptying and has the potential to impact the absorption of concomitantly administered oral medications.
  • Insulin Secretagogues or Insulin: Concomitant use may increase the risk of hypoglycemia, including severe hypoglycemia. Reducing dose of insulin secretagogue or insulin may be necessary.

Frequently Asked Questions

MOUNJARO 10 mg/0.5mL is used as an adjunct to diet and exercise to improve glycemic control in adults and pediatric patients 10 years of age and older with type 2 diabetes mellitus. It is also indicated to reduce the risk of major adverse cardiovascular events in adults with type 2 diabetes mellitus who are at high risk for these events.

Tirzepatide is a glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist. It enhances insulin secretion and reduces glucagon levels in a glucose-dependent manner, thereby lowering fasting and postprandial glucose concentrations, decreasing food intake, and reducing body weight in patients with type 2 diabetes mellitus.

The usual starting dosage of MOUNJARO is 2.5 mg injected subcutaneously once weekly. The dosage can be increased in 2.5 mg increments after at least 4 weeks on the current dose, up to a maximum of 15 mg for adults and 10 mg for pediatric patients 10 years of age and older. The prescriber will determine the appropriate dosage based on individual patient needs.

Based on animal studies, MOUNJARO may cause fetal harm. It is not recommended for use during pregnancy. The safety of MOUNJARO during breastfeeding has not been established. Patients should consult their healthcare provider for personalized advice.

To order MOUNJARO 10 mg/0.5mL from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets and will ask the buyer to confirm trade or institutional credentials. The team will then provide pricing, availability, shipping, and the necessary import paperwork.

MOUNJARO 10 mg/0.5mL is a dual GIP and GLP-1 receptor agonist, which distinguishes it from other diabetes medications that may target only one of these pathways. Its unique mechanism of action can provide additional benefits in glycemic control and weight reduction compared to other treatments.

MOUNJARO 10 mg/0.5mL should be stored in the refrigerator at 2°C to 8°C (36°F to 46°F). If needed, each single-dose pen or single-dose vial can be stored unrefrigerated at temperatures not to exceed 30°C (86°F) for up to a total of 21 days. Do not freeze MOUNJARO and protect it from heat and light.

MOUNJARO 10 mg/0.5mL is administered subcutaneously once weekly. It can be injected in the abdomen, thigh, or back of the upper arm. The injection site should be rotated with each dose. Patients should follow the instructions provided by their healthcare provider for proper administration.

The most serious risks associated with MOUNJARO 10 mg/0.5mL include acute pancreatitis, severe hypoglycemia when used with insulin secretagogues or insulin, hypersensitivity reactions, acute kidney injury due to volume depletion, and severe gastrointestinal adverse reactions. Patients should seek immediate medical attention if they experience any of these symptoms.

MOUNJARO 10 mg/0.5mL should not be used by patients with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2. It is also not recommended for patients with severe gastroparesis or a history of severe gastrointestinal disease. Patients should consult their healthcare provider to determine if MOUNJARO is appropriate for them.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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