Product image of MOUNJARO 12.5 mg (Tirzepatide) 12.5 mgx0.5 ml PFS supplied by GNH India

MOUNJARO 12.5 mg

Active Ingredient:
Tirzepatide
Form:
PFS
Brand:
MOUNJARO
Origin:
USA

MOUNJARO 12.5 mg (Tirzepatide PFS) 12.5 mgx0.5 ml

Tirzepatide, the active ingredient in MOUNJARO 12.5 mg, is a GIP/GLP-1 receptor agonist presented as a 12.5 mg/0.5 mL pre-filled syringe for subcutaneous use. It is indicated as an adjunct to diet and exercise to improve glycemic control in adults and pediatric patients 10 years of age and older with type 2 diabetes mellitus.

GNH India supplies MOUNJARO 12.5 mg as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide.

Strength

12.5 mgx0.5 ml

Pack Size

4s

Storage

2-8°

Manufacturer / TM Owner

LILLY ELI & CO

1
Pack/s
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Indications & Clinical Uses

MOUNJARO 12.5 mg is a GIP/GLP-1 receptor agonist used in the management of type 2 diabetes mellitus. It is indicated for:

  • Type 2 diabetes mellitus: Improves glycemic control in adults and pediatric patients 10 years of age and older when used as an adjunct to diet and exercise.

MOUNJARO 12.5 mg is not recommended for use in patients with severe gastroparesis or a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).

How It Works

  • Tirzepatide, the active ingredient in MOUNJARO 12.5 mg, activates both glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors. This dual action enhances insulin secretion, suppresses glucagon, slows gastric emptying, and reduces appetite, leading to improved glycemic control in patients with type 2 diabetes mellitus.

Side Effects

MOUNJARO 12.5 mg may cause various side effects, which can be categorized as common or serious.

Common Side Effects

  • Nausea
  • Diarrhea
  • Decreased appetite
  • Vomiting
  • Constipation
  • Dyspepsia
  • Abdominal pain

Serious or Rare Side Effects

  • Acute pancreatitis
  • Severe gastrointestinal adverse reactions
  • Hypersensitivity reactions, including anaphylaxis and angioedema
  • Tumors in the thyroid, including thyroid cancer
  • Dehydration leading to kidney problems
  • Hypoglycemia
  • Gallbladder problems

Precautions & Warnings

MOUNJARO 12.5 mg should be used with caution and certain precautions should be observed:

  • Avoid use in patients with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
  • Monitor for symptoms of pancreatitis, such as severe abdominal pain.
  • Ensure adequate hydration to prevent dehydration and potential kidney problems.
  • Monitor for signs of hypoglycemia, especially when used with other antidiabetic medications.
  • Use with caution in patients with a history of severe gastrointestinal disease.
  • Store at 2-8°C: Keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

MOUNJARO 12.5 mg may interact with other medications, which can be categorized as major or moderate interactions.

Major Interactions (Avoid)

  • Insulin and other antidiabetic medications: Increased risk of hypoglycemia.
  • Drugs that slow gastric emptying: May exacerbate gastrointestinal side effects.

Moderate Interactions (Monitor Closely)

  • Oral medications: May affect the absorption of oral medications due to delayed gastric emptying.
  • Diuretics: Increased risk of dehydration and kidney problems.
  • Corticosteroids: May affect blood glucose levels and increase the risk of hyperglycemia.

Frequently Asked Questions

MOUNJARO 12.5 mg is used as an adjunct to diet and exercise to improve glycemic control in adults and pediatric patients 10 years of age and older with type 2 diabetes mellitus. It is a GIP/GLP-1 receptor agonist that helps enhance insulin secretion, suppress glucagon, slow gastric emptying, and reduce appetite, leading to better management of blood sugar levels.

Tirzepatide, the active ingredient in MOUNJARO 12.5 mg, activates both glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors. This dual action enhances insulin secretion, suppresses glucagon, slows gastric emptying, and reduces appetite, leading to improved glycemic control in patients with type 2 diabetes mellitus.

The usual dose of MOUNJARO 12.5 mg is determined by the prescribing healthcare provider based on the patient's individual needs and response to the medication. It is important to follow the prescribed dosage and administration instructions provided by the healthcare provider.

The safety of MOUNJARO 12.5 mg during pregnancy or breastfeeding has not been established. It is important to consult with a healthcare provider before using this medication if you are pregnant, planning to become pregnant, or breastfeeding.

To order MOUNJARO 12.5 mg from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets. The team will ask you to confirm your trade or institutional credentials and will reply with pricing, availability, shipping, and the import paperwork.

MOUNJARO 12.5 mg is a GIP/GLP-1 receptor agonist, which distinguishes it from other classes of antidiabetic medications such as DPP-4 inhibitors, SGLT2 inhibitors, and insulin. Its dual action on GIP and GLP-1 receptors provides a multifaceted approach to glycemic control, which may offer benefits in terms of efficacy and side effect profile compared to other medications.

MOUNJARO 12.5 mg should be stored at 2-8°C, kept refrigerated, protected from light, and not frozen or shaken. Proper storage and handling are essential to maintain the medication's effectiveness and safety.

MOUNJARO 12.5 mg is administered as a subcutaneous injection using a pre-filled syringe. The injection is typically given once weekly, and the healthcare provider will instruct the patient on the proper administration technique.

The most serious risks associated with MOUNJARO 12.5 mg include acute pancreatitis, severe gastrointestinal adverse reactions, hypersensitivity reactions, tumors in the thyroid, dehydration leading to kidney problems, hypoglycemia, and gallbladder problems. Patients should be monitored for these risks and seek medical attention if any concerning symptoms occur.

MOUNJARO 12.5 mg should not be used by patients with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). It is also not recommended for patients with severe gastroparesis or those who are allergic to tirzepatide or any of the ingredients in MOUNJARO 12.5 mg.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

References

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