Product image of MOUNJARO 15 mg/.5mL (Tirzepatide) 15 mg/.5mL INJECTION, SOLUTION supplied by GNH India

MOUNJARO 15 mg/.5mL

Active Ingredient:
Tirzepatide
Form:
INJECTION, SOLUTION
Brand:
MOUNJARO
Origin:
USA

MOUNJARO 15 mg/.5mL (Tirzepatide INJECTION, SOLUTION) 15 mg/.5mL

Tirzepatide, the active ingredient in MOUNJARO 15 mg/0.5 mL, is a glucose-dependent insulinotropic polypeptide (GIP) receptor and glucagon-like peptide-1 (GLP-1) receptor agonist presented as a 15 mg/0.5 mL injection, solution for subcutaneous use. It is used as an adjunct to diet and exercise to improve glycemic control in adults and pediatric patients 10 years of age and older with type 2 diabetes mellitus.

GNH India supplies MOUNJARO 15 mg/0.5 mL as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide.

Strength

15 mg/.5mL

Pack Size

4 SYRINGE in 1 CARTON (0002-1457-80) / .5 mL in 1 SYRINGE (0002-1457-01)

Manufacturer / TM Owner

Eli Lilly and Company

1
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Indications & Clinical Uses

MOUNJARO 15 mg/0.5 mL is indicated for the management of type 2 diabetes mellitus and related metabolic conditions.

  • Type 2 diabetes mellitus: Improves glycemic control in adults and pediatric patients 10 years of age and older.
  • Major adverse cardiovascular events: Reduces the risk of cardiovascular death, non-fatal myocardial infarction, or non-fatal stroke in adults with type 2 diabetes mellitus who are at high risk for these events.

How It Works

  • Tirzepatide, the active ingredient in MOUNJARO, is a dual GIP and GLP-1 receptor agonist. It selectively binds to and activates both the GIP and GLP-1 receptors, enhancing first- and second-phase insulin secretion and reducing glucagon levels in a glucose-dependent manner. This action lowers fasting and postprandial glucose concentrations, decreases food intake, and reduces body weight in patients with type 2 diabetes mellitus.

Side Effects

MOUNJARO 15 mg/0.5 mL may cause various side effects, ranging from common to serious.

Common Side Effects

  • Nausea
  • Diarrhea
  • Decreased appetite
  • Vomiting
  • Constipation
  • Dyspepsia
  • Abdominal pain

Serious or Rare Side Effects

  • Acute pancreatitis
  • Hypoglycemia when used with insulin secretagogues or insulin
  • Hypersensitivity reactions, including anaphylaxis and angioedema
  • Acute kidney injury due to volume depletion
  • Severe gastrointestinal adverse reactions
  • Diabetic retinopathy complications in patients with a history of diabetic retinopathy
  • Acute gallbladder disease

Precautions & Warnings

MOUNJARO 15 mg/0.5 mL should be used with caution in certain patient populations and conditions.

  • Acute pancreatitis: Discontinue if suspected.
  • Hypoglycemia: Concomitant use with insulin secretagogues or insulin may increase the risk of hypoglycemia.
  • Hypersensitivity reactions: Discontinue if suspected and promptly seek medical advice.
  • Acute kidney injury: Monitor renal function in patients reporting adverse reactions that could lead to volume depletion.
  • Severe gastrointestinal adverse reactions: Not recommended in patients with severe gastroparesis.
  • Store at 2-8°C: Keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

MOUNJARO 15 mg/0.5 mL may interact with other medications, potentially affecting their absorption or efficacy.

Major Interactions (Avoid)

  • Oral medications: MOUNJARO delays gastric emptying and has the potential to impact the absorption of concomitantly administered oral medications.

Moderate Interactions (Monitor Closely)

  • Insulin secretagogues or insulin: Concomitant use may increase the risk of hypoglycemia.
  • Oral contraceptives: Advise females using oral contraceptives to switch to a non-oral contraceptive method or add a barrier method of contraception for 4 weeks after initiation and for 4 weeks after each dose escalation.

Frequently Asked Questions

MOUNJARO 15 mg/0.5 mL is used as an adjunct to diet and exercise to improve glycemic control in adults and pediatric patients 10 years of age and older with type 2 diabetes mellitus. It is also indicated to reduce the risk of major adverse cardiovascular events in adults with type 2 diabetes mellitus who are at high risk for these events.

Tirzepatide, the active ingredient in MOUNJARO, is a dual GIP and GLP-1 receptor agonist. It selectively binds to and activates both the GIP and GLP-1 receptors, enhancing insulin secretion and reducing glucagon levels in a glucose-dependent manner. This action helps lower blood sugar levels and reduce body weight.

The usual dose of MOUNJARO 15 mg/0.5 mL is determined by the prescriber based on the patient's individual needs and response to treatment. The recommended starting dosage is 2.5 mg injected subcutaneously once weekly, with dose increases in 2.5 mg increments after at least 4 weeks on the current dose.

Based on animal studies, MOUNJARO 15 mg/0.5 mL may cause fetal harm. It is not recommended for use during pregnancy. The safety of MOUNJARO during breastfeeding has not been established. Patients should consult their healthcare provider for personalized advice.

To order MOUNJARO 15 mg/0.5 mL from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets and will ask the buyer to confirm trade or institutional credentials. The team will then reply with pricing, availability, shipping, and the import paperwork.

MOUNJARO 15 mg/0.5 mL is a dual GIP and GLP-1 receptor agonist, which differentiates it from other diabetes medications that may target only one of these receptors or use different mechanisms to lower blood sugar levels. Its dual action provides a unique approach to glycemic control and weight reduction.

MOUNJARO 15 mg/0.5 mL should be stored in the refrigerator at 2°C to 8°C (36°F to 46°F). If needed, each single-dose pen or single-dose vial can be stored unrefrigerated at temperatures not to exceed 30°C (86°F) for up to 21 days. Do not freeze MOUNJARO and do not use if frozen. Store in the original carton to protect from light.

MOUNJARO 15 mg/0.5 mL is administered subcutaneously once weekly at any time of day, with or without meals. It can be injected in the abdomen, thigh, or have another person inject in the back of the upper arm. Rotate injection sites with each dose.

The most serious risks to watch for with MOUNJARO 15 mg/0.5 mL include acute pancreatitis, severe hypoglycemia when used with insulin secretagogues or insulin, hypersensitivity reactions, acute kidney injury due to volume depletion, severe gastrointestinal adverse reactions, and diabetic retinopathy complications in patients with a history of diabetic retinopathy.

MOUNJARO 15 mg/0.5 mL should not be used by patients with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2. It is also not recommended for patients with severe gastroparesis or a history of severe gastrointestinal disease.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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