Product image of MOUNJARO 2.5 mg/.5mL (Tirzepatide) 2.5 mg/.5mL INJECTION, SOLUTION supplied by GNH India

MOUNJARO 2.5 mg/.5mL

Active Ingredient:
Tirzepatide
Form:
INJECTION, SOLUTION
Brand:
MOUNJARO
Origin:
USA

MOUNJARO 2.5 mg/.5mL (Tirzepatide INJECTION, SOLUTION) 2.5 mg/.5mL

Tirzepatide, the active ingredient in MOUNJARO 2.5 mg/0.5mL, is a glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist presented as a 2.5 mg/0.5mL injection, solution for subcutaneous use. It is indicated as an adjunct to diet and exercise to improve glycemic control in adults and pediatric patients 10 years of age and older with type 2 diabetes mellitus.

GNH India supplies MOUNJARO 2.5 mg/0.5mL as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide.

Strength

2.5 mg/.5mL

Pack Size

4 SYRINGE in 1 CARTON (0002-1506-80) / .5 mL in 1 SYRINGE (0002-1506-01)

Manufacturer / TM Owner

Eli Lilly and Company

1
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Indications & Clinical Uses

MOUNJARO 2.5 mg/0.5mL is a GLP-1 receptor agonist used in the management of type 2 diabetes mellitus.

  • Type 2 diabetes mellitus: Improves glycemic control in adults and pediatric patients 10 years of age and older as an adjunct to diet and exercise.
  • Weight management: As an adjunct to a reduced-calorie diet and increased physical activity for weight management in adults with an initial Body Mass Index (BMI) of 30 kg/m² or greater (obesity) or 27 kg/m² to < 30 kg/m² (overweight) in the presence of at least one weight-related comorbid condition.

How It Works

  • Tirzepatide, the active ingredient in MOUNJARO, is a GIP and GLP-1 receptor agonist. It selectively binds to and activates both the GIP and GLP-1 receptors, enhancing first- and second-phase insulin secretion and reducing glucagon levels in a glucose-dependent manner. This dual action helps to lower fasting and postprandial glucose concentrations, decrease food intake, and reduce body weight in patients with type 2 diabetes mellitus.

Side Effects

MOUNJARO 2.5 mg/0.5mL may cause side effects, ranging from common to serious.

Common Side Effects

  • Nausea
  • Diarrhea
  • Decreased appetite
  • Vomiting
  • Constipation
  • Indigestion
  • Abdominal pain
  • Dizziness

Serious or Rare Side Effects

  • Acute pancreatitis
  • Hypoglycemia when used with insulin secretagogues or insulin
  • Hypersensitivity reactions, including anaphylaxis and angioedema
  • Acute kidney injury due to volume depletion
  • Severe gastrointestinal adverse reactions
  • Diabetic retinopathy complications in patients with a history of diabetic retinopathy
  • Acute gallbladder disease

Precautions & Warnings

MOUNJARO 2.5 mg/0.5mL should be used with caution and certain precautions should be observed.

  • Pancreatitis: Discontinue if pancreatitis is suspected.
  • Hypoglycemia: Monitor blood glucose levels when used with insulin secretagogues or insulin.
  • Hypersensitivity: Discontinue if serious hypersensitivity reactions occur.
  • Renal function: Monitor in patients reporting adverse reactions that could lead to volume depletion.
  • Gastrointestinal conditions: Not recommended in patients with severe gastroparesis.
  • Diabetic retinopathy: Monitor patients with a history of diabetic retinopathy for progression.
  • Store at 2-8°C: Keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

MOUNJARO 2.5 mg/0.5mL may interact with other medications, requiring careful monitoring.

Major Interactions (Avoid)

  • Insulin secretagogues: Increased risk of hypoglycemia.
  • Insulin: Increased risk of hypoglycemia.

Moderate Interactions (Monitor Closely)

  • Oral medications: MOUNJARO delays gastric emptying and may impact the absorption of concomitantly administered oral medications.
  • Other GLP-1 receptor agonists: Potential for additive gastrointestinal side effects.
  • Other medications affecting gastrointestinal motility: Potential for additive gastrointestinal side effects.

Frequently Asked Questions

MOUNJARO 2.5 mg/0.5mL is used as an adjunct to diet and exercise to improve glycemic control in adults and pediatric patients 10 years of age and older with type 2 diabetes mellitus. It is also indicated for weight management in adults with obesity or overweight with at least one weight-related comorbid condition.

Tirzepatide, the active ingredient in MOUNJARO, is a GIP and GLP-1 receptor agonist. It selectively binds to and activates both the GIP and GLP-1 receptors, enhancing insulin secretion and reducing glucagon levels in a glucose-dependent manner. This helps to lower blood sugar levels and reduce body weight.

The recommended starting dosage of MOUNJARO is 2.5 mg injected subcutaneously once weekly. After 4 weeks, the dosage can be increased to 5 mg once weekly. Further dose increases can be made in 2.5 mg increments after at least 4 weeks on the current dose, as determined by the prescribing healthcare provider.

The safety of MOUNJARO during pregnancy or breastfeeding has not been established. It is important to consult with a healthcare provider to discuss the potential risks and benefits before using MOUNJARO in these situations.

To order MOUNJARO 2.5 mg/0.5mL from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets. The team will ask you to confirm your trade or institutional credentials and will reply with pricing, availability, shipping, and the necessary import paperwork.

MOUNJARO is a dual GIP and GLP-1 receptor agonist, which distinguishes it from other GLP-1 receptor agonists that only target the GLP-1 receptor. This dual action may provide additional benefits in glycemic control and weight management compared to other medications in its class.

MOUNJARO should be stored in the refrigerator between 36°F to 46°F (2°C to 8°C). It can be stored at room temperature up to 86°F (30°C) for up to 21 days. Do not freeze MOUNJARO. Store it in the original carton to protect from light.

MOUNJARO is administered as a subcutaneous injection once weekly. The injection should be given in the abdomen, thigh, or upper arm, and the injection site should be rotated each week. It is important to follow the instructions provided by the healthcare provider and the patient information leaflet for proper administration.

The most serious risks associated with MOUNJARO include acute pancreatitis, severe hypoglycemia when used with insulin secretagogues or insulin, serious hypersensitivity reactions, acute kidney injury due to volume depletion, and severe gastrointestinal adverse reactions. Patients should be monitored for these risks and seek medical advice if they occur.

MOUNJARO should not be used by patients with a personal or family history of medullary thyroid carcinoma, multiple endocrine neoplasia syndrome type 2, or a history of severe gastrointestinal disease. It is also not recommended for patients with severe gastroparesis. Always consult with a healthcare provider to determine if MOUNJARO is appropriate for you.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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