Product image of NITROGLYCERIN 20 mg/g (Nitroglycerin) 20 mg/g OINTMENT supplied by GNH India

NITROGLYCERIN 20 mg/g

Active Ingredient:
Nitroglycerin
Form:
OINTMENT
Brand:
NITROGLYCERIN
Origin:
USA

NITROGLYCERIN 20 mg/g (Nitroglycerin OINTMENT) 20 mg/g

Nitroglycerin, the active ingredient in NITROGLYCERIN 20 mg/g, is an organic nitrate presented as a 20 mg/g ointment for topical use. It is used to prevent angina pectoris in patients with coronary artery disease.

GNH India supplies NITROGLYCERIN 20 mg/g as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide.

Strength

20 mg/g

Pack Size

48 POUCH in 1 CARTON (21922-054-47) / 1 g in 1 POUCH (21922-054-59)

Manufacturer / TM Owner

Encube Ethicals Private Limited

1
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Indications & Clinical Uses

NITROGLYCERIN 20 mg/g ointment is used to manage cardiovascular conditions, particularly angina pectoris. It helps to prevent episodes of chest pain by improving blood flow to the heart.

  • Angina Pectoris: Prevents episodes of chest pain in patients with coronary artery disease.
  • Anal Fissures: Treats pain associated with anal fissures by relaxing anal tissues and reducing pressure.

How It Works

  • Nitroglycerin bioconverts to nitric oxide, which causes vascular smooth muscle relaxation and vasodilation. This reduces myocardial oxygen demand by improving blood flow to the heart, thereby preventing angina attacks and alleviating pain associated with anal fissures.

Side Effects

NITROGLYCERIN 20 mg/g ointment may cause side effects, ranging from mild to severe. Common Side Effects:

  • Lightheadedness
  • Dizziness
  • Redness or irritation of the skin
  • Flushing
  • Headache

Serious or Rare Side Effects

  • Slow heartbeat
  • Worsening chest pain
  • Fainting
  • Rash, hives, or itching
  • Difficulty breathing or swallowing

Precautions & Warnings

NITROGLYCERIN 20 mg/g ointment should be used with caution in certain conditions. Inform your healthcare provider if you have any of the following:

  • Anemia or increased pressure in the brain or skull: May be advised not to use the ointment.
  • Taking riociguat or PDE-5 inhibitors: May be advised not to use the ointment.
  • Dehydration, recent heart attack, low blood pressure, heart failure, or migraines: Use with caution.
  • Apply the ointment as directed: Follow the prescribed dosage and application instructions.
  • Store at room temperature: Keep the ointment tightly closed and away from excess heat and moisture.

Avoid Interactions

NITROGLYCERIN 20 mg/g ointment may interact with other medications, potentially altering its effects or increasing the risk of side effects. Major Interactions (Avoid):

  • Riociguat (Adempas): Avoid concurrent use due to the risk of severe hypotension.
  • PDE-5 inhibitors (e.g., sildenafil, tadalafil): Avoid concurrent use due to the risk of severe hypotension.

Moderate Interactions (Monitor Closely)

  • Aspirin: May enhance the hypotensive effects of nitroglycerin.
  • Beta blockers (e.g., propranolol, metoprolol): May reduce the effectiveness of nitroglycerin.
  • Calcium channel blockers (e.g., amlodipine, diltiazem): May enhance the hypotensive effects of nitroglycerin.
  • Ergot-type medications (e.g., ergotamine, dihydroergotamine): May reduce the effectiveness of nitroglycerin.

Frequently Asked Questions

NITROGLYCERIN 20 mg/g ointment is used to prevent episodes of angina pectoris in patients with coronary artery disease. It works by relaxing the blood vessels, which improves blood flow to the heart and reduces the risk of chest pain. Additionally, it is used to treat pain associated with anal fissures by relaxing the anal tissues and reducing pressure.

Nitroglycerin bioconverts to nitric oxide, which causes vascular smooth muscle relaxation and vasodilation. This reduces myocardial oxygen demand by improving blood flow to the heart, thereby preventing angina attacks and alleviating pain associated with anal fissures.

The dosage of NITROGLYCERIN 20 mg/g ointment is determined by a healthcare provider based on the patient's condition and response to treatment. It is typically applied twice a day for angina prevention and every 12 hours for up to 3 weeks for anal fissure pain. Always follow the prescribed dosage and application instructions.

The safety of NITROGLYCERIN 20 mg/g ointment during pregnancy or breastfeeding is not well established. It is important to consult with a healthcare provider before using this medication if you are pregnant, planning to become pregnant, or breastfeeding.

To order NITROGLYCERIN 20 mg/g ointment from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets. The team will ask you to confirm your trade or institutional credentials and will provide pricing, availability, shipping, and the necessary import paperwork.

NITROGLYCERIN 20 mg/g ointment is a topical form of nitroglycerin, which is a well-established treatment for preventing angina attacks. It works by relaxing the blood vessels and improving blood flow to the heart. Compared to other forms of nitroglycerin, such as tablets or sprays, the ointment provides a sustained release of the medication, which can be beneficial for long-term prevention of angina.

NITROGLYCERIN 20 mg/g ointment should be stored at room temperature, away from excess heat and moisture. Keep the ointment tube tightly closed and protect it from light. Do not refrigerate or freeze the ointment. Always follow the storage instructions provided with the medication.

NITROGLYCERIN 20 mg/g ointment is applied topically to the skin. For angina prevention, it is usually applied twice a day, once in the morning and again 6 hours later. For anal fissure pain, it is applied every 12 hours for up to 3 weeks. Follow the application instructions provided by your healthcare provider.

The most serious risks associated with NITROGLYCERIN 20 mg/g ointment include severe hypotension, worsening chest pain, fainting, and allergic reactions such as rash, hives, or difficulty breathing. If you experience any of these symptoms, seek immediate medical attention.

NITROGLYCERIN 20 mg/g ointment should not be used by individuals who are allergic to nitroglycerin or any of the ingredients in the ointment. It should also be avoided by patients taking riociguat or PDE-5 inhibitors, as well as those with certain medical conditions such as anemia or increased pressure in the brain or skull. Always consult with a healthcare provider before using this medication.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

References

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