Orfadin 20 mg (Nitisinone CAPSULE) 20 MG

ORFADIN 20 MG capsules contain nitisinone, a medication used to manage certain metabolic disorders. This oral medication is designed to help regulate specific enzyme deficiencies, supporting overall metabolic health.

Strength

20 MG

Pack Size

Manufacturer / TM Owner

SWEDISH ORPHAN BIOVITRUM AB (PUBL)

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Indications & Clinical Uses

ORFADIN 20 MG capsules are primarily used in the management of hereditary tyrosinemia type 1, a rare metabolic disorder. Nitisinone works by inhibiting the production of toxic substances that can build up in the body due to this condition. It is often prescribed as part of a comprehensive treatment plan that includes dietary restrictions and other supportive therapies.

Side Effects

Common effects of ORFADIN 20 MG capsules may include gastrointestinal discomfort, such as nausea or vomiting. Some individuals might experience fatigue or drowsiness. These effects can vary from person to person and are generally mild to moderate in nature.

Precautions & Warnings

ORFADIN 20 MG capsules should be handled with care, especially by individuals with known allergies to nitisinone or any of the inactive ingredients. It is important to follow the prescribed dosage and administration instructions provided by a healthcare professional. Regular monitoring may be necessary to ensure the medication's effectiveness and safety.

Avoid Interactions

Nitisinone can interact with certain medications, including those metabolized by the liver's cytochrome P450 enzymes. It is advisable to inform your healthcare provider about all medications you are taking to avoid potential interactions. Alcohol consumption should be discussed with a healthcare professional, as it may affect the metabolism of nitisinone.

Frequently Asked Questions

ORFADIN 20 MG capsules are used to manage hereditary tyrosinemia type 1, a metabolic disorder that affects the body's ability to break down tyrosine.

ORFADIN 20 MG capsules are taken orally, typically once daily. The exact dosage and administration instructions should be followed as prescribed by a healthcare professional.

Common side effects may include gastrointestinal discomfort, nausea, vomiting, fatigue, and drowsiness. These effects are generally mild to moderate.

Nitisinone can interact with certain medications, so it is important to inform your healthcare provider about all medications you are taking.

Long-term use of ORFADIN 20 MG should be monitored by a healthcare professional to ensure its continued safety and effectiveness.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated: 29 Jul 2026

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