Orkambi 125 mg (Ivacaftor TABLET) 125 MG

Orkambi 125 mg tablets contain ivacaftor, a medication used to treat cystic fibrosis. This oral medication is designed to improve lung function and reduce symptoms associated with the condition.

Strength

125 MG

Pack Size

28/112

Manufacturer / TM Owner

VERTEX PHARMACEUTICALS (CANADA) INCORPORATED

Select Quantity

Pack/s

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

First Name

Last Name

Phone

Delivery Country

Delivery PostCode/Zipcode

Select Your Profile

I have read and agree to the terms & conditions, including the privacy policy, return policy, and usage terms as applicable to this request.

Indications & Clinical Uses

Orkambi 125 mg tablets are primarily used in the management of cystic fibrosis in patients who have specific genetic mutations. Ivacaftor, the active ingredient, works by helping the cystic fibrosis transmembrane conductance regulator (CFTR) protein function more effectively. This can lead to improved lung function and reduced symptoms such as coughing and shortness of breath. Orkambi is often prescribed as part of a comprehensive treatment plan for cystic fibrosis.

Side Effects

Common effects of Orkambi 125 mg tablets may include headaches, stomach pain, and dizziness. Some users might experience changes in liver function, so regular monitoring is advised. It's important to discuss any persistent or severe side effects with a healthcare provider.

Precautions & Warnings

Orkambi 125 mg tablets should be used with caution in patients with liver disease or a history of liver problems. It is essential to follow the prescribed dosage and administration instructions provided by a healthcare professional. Always inform your healthcare provider about any other medications you are taking to avoid potential interactions.

Avoid Interactions

Orkambi 125 mg tablets may interact with certain medications, including those that are metabolized by the liver's cytochrome P450 enzymes. It is important to avoid grapefruit and grapefruit juice, as they can affect the metabolism of ivacaftor. Always consult a healthcare provider before starting or stopping any medication while taking Orkambi.

Frequently Asked Questions

Orkambi 125 mg tablets are used to treat cystic fibrosis in patients with specific genetic mutations. They help improve lung function and reduce symptoms.

Orkambi 125 mg tablets are taken orally, typically with fat-containing food to enhance absorption. Follow the dosage instructions provided by your healthcare provider.

Common side effects may include headaches, stomach pain, and dizziness. Some users might experience changes in liver function, so regular monitoring is advised.

Orkambi 125 mg may interact with certain medications, especially those metabolized by the liver. Always consult a healthcare provider before combining medications.

Orkambi 125 mg should be used with caution in patients with liver disease. Always inform your healthcare provider about your medical history and current medications.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated: 29 Jul 2026

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.