Pain Relief Acetaminophen PM Extra Strength 500 mg/1 (Acetaminophen and Diphenhydramine HCl TABLET, FILM COATED) 500 mg/1

Pain Relief Acetaminophen PM Extra Strength 500 mg/1 combines acetaminophen and diphenhydramine HCl for dual-action relief. This oral tablet is designed to help manage pain and promote sleep, making it a popular choice for nighttime discomfort.

Strength

500 mg/1

Pack Size

1 BOTTLE, PLASTIC in 1 CARTON (11822-2350-2) / 100 TABLET, FILM COATED in 1 BOTTLE, PLASTIC

Manufacturer / TM Owner

Rite Aid Corporation

Select Quantity

Pack/s

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Indications & Clinical Uses

Pain Relief Acetaminophen PM Extra Strength 500 mg/1 is commonly used for managing mild to moderate pain, such as headaches, muscle aches, and arthritis. The inclusion of diphenhydramine HCl also aids in promoting sleep, making it suitable for those who experience discomfort that interferes with rest. This medication is often sought after for its dual-action benefits, addressing both pain and sleep disturbances.

Side Effects

Users of Pain Relief Acetaminophen PM Extra Strength 500 mg/1 may experience reduced pain and improved sleep quality. The acetaminophen component works to alleviate discomfort, while the diphenhydramine HCl helps induce drowsiness. Some individuals might notice mild side effects, but these are generally temporary and subside as the body adjusts to the medication.

Precautions & Warnings

It is important to handle Pain Relief Acetaminophen PM Extra Strength 500 mg/1 with care, especially if you have any known allergies to acetaminophen or diphenhydramine HCl. Always follow the recommended guidelines for use and consult a healthcare professional if you have any underlying health conditions or are taking other medications. Store the tablets in a cool, dry place away from direct sunlight.

Avoid Interactions

Pain Relief Acetaminophen PM Extra Strength 500 mg/1 may interact with certain medications, including other pain relievers, sedatives, and antidepressants. Alcohol consumption should be avoided as it can enhance the sedative effects of diphenhydramine HCl. Always inform your healthcare provider about all the medications you are taking to avoid potential interactions.

Frequently Asked Questions

This medication is used for managing mild to moderate pain and promoting sleep, making it suitable for nighttime discomfort.

Follow the instructions on the packaging or as advised by your healthcare provider. Typically, it is taken orally with water.

Consult your healthcare provider before combining it with other medications to avoid potential interactions.

Some users may experience mild side effects such as drowsiness, dizziness, or dry mouth.

Long-term use should be discussed with a healthcare professional to ensure safety and effectiveness.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated: 29 Jul 2026

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