Polymyxin B 500000 [USP'U]/1 (Polymyxin B Sulfate INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION) 500000 [USP'U]/1

Polymyxin B Sulfate is an injectable antibiotic used to treat severe bacterial infections. This lyophilized powder is reconstituted for intramuscular, intrathecal, or intravenous administration. Learn more about its uses and effects.

Strength

500000 [USP'U]/1

Pack Size

10 VIAL in 1 CARTON (25021-196-10) / 1 INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION in 1 VIAL

Manufacturer / TM Owner

Sagent Pharmaceuticals

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Indications & Clinical Uses

Polymyxin B Sulfate is primarily used to treat serious bacterial infections, particularly those caused by gram-negative bacteria. It is often employed when other antibiotics are ineffective. The drug is administered via injection, making it suitable for hospital settings. What is Polymyxin B used for? It is typically prescribed for infections that do not respond to other treatments, including certain types of meningitis and sepsis.

Side Effects

Common effects of Polymyxin B Sulfate may include localized pain or irritation at the injection site. Some individuals might experience systemic reactions such as fever or chills. These effects are generally mild and temporary, but severe reactions are possible and should be reported to a healthcare provider immediately.

Precautions & Warnings

Polymyxin B Sulfate should be handled with care, as it is a potent antibiotic. It is essential to follow proper reconstitution and administration guidelines to avoid complications. Patients with a history of allergic reactions to polymyxins should avoid this medication. Always consult a healthcare professional before use.

Avoid Interactions

Polymyxin B Sulfate may interact with other medications, particularly other antibiotics or neuromuscular blocking agents. It is important to inform your healthcare provider about all medications you are taking to avoid potential interactions. Alcohol and certain other substances may also affect the efficacy of this drug.

Frequently Asked Questions

Polymyxin B Sulfate is used to treat severe bacterial infections, especially those caused by gram-negative bacteria that are resistant to other antibiotics.

Polymyxin B Sulfate is administered via injection, which can be intramuscular, intrathecal, or intravenous, depending on the specific medical condition being treated.

Common side effects may include pain or irritation at the injection site, fever, and chills. Severe reactions are possible and should be reported to a healthcare provider.

Polymyxin B Sulfate may interact with other medications, so it is important to consult a healthcare provider before combining it with other treatments.

Individuals with a history of allergic reactions to polymyxins should avoid using Polymyxin B Sulfate. Always consult a healthcare professional before starting this medication.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated: 29 Jul 2026

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