Protamine Sulfate Injection USP 10 mg (Protamine Sulfate SOLUTION) 10 MG

Protamine Sulfate Injection USP 10 MG is a medication used to reverse the effects of heparin. This intravenous solution is manufactured by Sandoz Canada Incorporated and is available in 10x5ml and 1x25ml packs.

Strength

10 MG

Pack Size

10X5ML, 1X25ML

Manufacturer / TM Owner

SANDOZ CANADA INCORPORATED

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Pack/s

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Indications & Clinical Uses

Protamine Sulfate Injection is primarily used to neutralize the anticoagulant effects of heparin. It is often administered in medical settings where heparin has been used to prevent or treat blood clots. The medication works by binding to heparin, effectively reducing its ability to thin the blood. This can be crucial in situations where bleeding risks need to be managed carefully.

Side Effects

When administered, Protamine Sulfate Injection can cause a range of effects, including a reduction in bleeding time. Common side effects may include mild allergic reactions, such as itching or hives. In some cases, more severe reactions like difficulty breathing or low blood pressure can occur, although these are less frequent. It is important to monitor patients closely after administration to ensure safety.

Precautions & Warnings

Protamine Sulfate Injection should be used with caution in individuals with a history of allergic reactions to fish proteins, as protamine is derived from fish. It is also important to ensure that the correct dosage is administered to avoid potential complications. Patients should be monitored for any signs of adverse reactions, and medical professionals should be prepared to manage any severe reactions promptly.

Avoid Interactions

Protamine Sulfate Injection can interact with other medications, particularly those that affect blood clotting. It is important to inform healthcare providers about all medications being taken to avoid potential interactions. Additionally, caution should be exercised when using this medication in conjunction with other anticoagulants or medications that affect blood pressure.

Frequently Asked Questions

Protamine Sulfate Injection is used to reverse the anticoagulant effects of heparin, helping to manage bleeding risks.

Protamine Sulfate Injection is administered intravenously, typically in a medical setting.

Common side effects may include mild allergic reactions, such as itching or hives, and in rare cases, more severe reactions like difficulty breathing.

Protamine Sulfate Injection can interact with other medications, so it is important to inform healthcare providers about all medications being taken.

Individuals with a history of allergic reactions to fish proteins should use Protamine Sulfate Injection with caution.

Editorial & Trust Signals

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical wholesaler & exporter

Last updated: 17 Jun 2026

References

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