Product image of Septra Injection 80 mg (Sulfamethoxazole) 80 MG SOLUTION supplied by GNH India

Septra Injection 80 mg

Active Ingredient:
Sulfamethoxazole
Form:
SOLUTION
Brand:
SEPTRA INJECTION
Origin:
CANADA

Septra Injection 80 mg (Sulfamethoxazole SOLUTION) 80 MG

Sulfamethoxazole, the active ingredient in SEPTRA INJECTION, is a sulfonamide presented as an 80 mg injection solution for intravenous use. It is used to treat a range of bacterial infections, including urinary tract infections, respiratory tract infections, and skin and soft tissue infections. GNH India supplies SEPTRA INJECTION as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals and clinics worldwide.

SEPTRA INJECTION is a combination antibiotic that includes trimethoprim, enhancing its effectiveness against bacterial infections. It is administered intravenously under medical supervision to ensure proper dosage and administration.

Strength

80 MG

Pack Size

5ML

Manufacturer / TM Owner

ASPEN PHARMACARE CANADA INC.

1
Pack/s
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Indications & Clinical Uses

SEPTRA INJECTION is used to treat various bacterial infections by targeting the bacterial folate synthesis pathway. It is effective in managing the following conditions:

  • Urinary tract infections: Treats infections in the urinary system, including bladder and kidney infections.
  • Respiratory tract infections: Effective against infections such as pneumonia and bronchitis.
  • Skin and soft tissue infections: Used to treat infections like cellulitis and abscesses.

How It Works

  • SEPTRA INJECTION works by inhibiting the bacterial enzymes dihydropteroate synthase and dihydrofolate reductase, which are essential for the synthesis of folic acid in bacteria. By blocking these enzymes, the combination of sulfamethoxazole and trimethoprim disrupts the bacterial folate synthesis pathway, leading to the inhibition of bacterial growth and replication.

Side Effects

SEPTRA INJECTION may cause various side effects, ranging from common to serious. Common Side Effects:

  • Nausea and vomiting
  • Diarrhea
  • Rash or skin irritation
  • Headache
  • Loss of appetite
  • Mild fatigue

Serious or Rare Side Effects

  • Severe skin reactions, such as Stevens-Johnson syndrome and toxic epidermal necrolysis
  • Blood dyscrasias, including agranulocytosis, thrombocytopenia, and anemia
  • Allergic reactions, which may include swelling, difficulty breathing, and rash
  • Kidney problems, including crystalluria and renal failure
  • Liver toxicity, which may manifest as jaundice or abnormal liver function tests

Precautions & Warnings

SEPTRA INJECTION should be used with caution and under medical supervision. Important precautions include:

  • Allergy: Not recommended for individuals allergic to sulfa drugs or trimethoprim.
  • Pregnancy: Use with caution, especially near term, as it may cause harm to the fetus.
  • Breastfeeding: Use with caution, as it may pass into breast milk.
  • Kidney or liver impairment: Dosage adjustments may be necessary.
  • Blood disorders: Monitor for signs of blood dyscrasias.
  • Sun sensitivity: Avoid prolonged sun exposure, as this medication may increase sun sensitivity.
  • Store at room temperature: Protect from light and keep out of reach of children.

Avoid Interactions

SEPTRA INJECTION may interact with other medications, potentially altering its effectiveness or increasing the risk of side effects. Major Interactions (Avoid):

  • Warfarin: May increase the risk of bleeding.
  • Phenytoin: May increase the risk of side effects such as confusion and seizures.
  • Methotrexate: May increase the risk of bone marrow suppression.

Moderate Interactions (Monitor Closely)

  • Cyclosporine: May increase the risk of nephrotoxicity.
  • Diuretics: May increase the risk of electrolyte imbalances.
  • Anti-seizure drugs: May alter the effectiveness of SEPTRA INJECTION.

Frequently Asked Questions

SEPTRA INJECTION is used to treat a range of bacterial infections, including urinary tract infections, respiratory tract infections, and skin and soft tissue infections. It is administered intravenously under medical supervision to ensure proper dosage and administration.

Sulfamethoxazole works by inhibiting the bacterial enzymes dihydropteroate synthase and dihydrofolate reductase, which are essential for the synthesis of folic acid in bacteria. By blocking these enzymes, it disrupts the bacterial folate synthesis pathway, leading to the inhibition of bacterial growth and replication.

The dosage of SEPTRA INJECTION is determined by a healthcare professional based on the type and severity of the infection, as well as the patient's overall health. It is important to follow the prescribed dosage and administration instructions provided by your doctor.

SEPTRA INJECTION should be used with caution during pregnancy, especially near term, as it may cause harm to the fetus. It should also be used with caution during breastfeeding, as it may pass into breast milk. Always consult your healthcare provider before using this medication if you are pregnant or breastfeeding.

To order SEPTRA INJECTION from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets and will ask the buyer to confirm trade or institutional credentials. The team will reply with pricing, availability, shipping, and the import paperwork.

SEPTRA INJECTION is a combination antibiotic that includes sulfamethoxazole and trimethoprim, making it effective against a wide range of bacterial infections. Compared to other antibiotics, it is particularly useful in treating infections where resistance to single-agent antibiotics is a concern.

SEPTRA INJECTION should be stored at room temperature between 15° and 30°C and protected from light. It is important to keep the medication out of reach of children and to follow the storage instructions provided on the packaging.

SEPTRA INJECTION is administered intravenously under medical supervision. It is typically given as a slow IV infusion over 60–90 minutes. The dosage and administration schedule are determined by a healthcare professional based on the type and severity of the infection.

The most serious risks associated with SEPTRA INJECTION include severe skin reactions, blood dyscrasias, allergic reactions, kidney problems, and liver toxicity. It is important to monitor for these side effects and to seek medical attention if they occur.

SEPTRA INJECTION should not be used by individuals who are allergic to sulfa drugs or trimethoprim. It should also be used with caution in individuals with marked liver damage, severe renal insufficiency, megaloblastic anemia due to folate deficiency, and in pregnant women, especially near term, and infants under 2 months old.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

References

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