Product image of Tramadol Hydrochloride 200 mg/1 (Tramadol Hydrochloride) 200 mg/1 TABLET, FILM COATED, EXTENDED RELEASE supplied by GNH India

Tramadol Hydrochloride 200 mg/1

Active Ingredient:
Tramadol Hydrochloride
Form:
TABLET, FILM COATED, EXTENDED RELEASE
Brand:
Tramadol Hydrochloride
Origin:
USA

Tramadol Hydrochloride 200 mg/1 (Tramadol Hydrochloride TABLET, FILM COATED, EXTENDED RELEASE) 200 mg/1

Tramadol Hydrochloride, the active ingredient in Tramadol Hydrochloride 200 mg/1, is an opioid analgesic presented as a 200 mg/1 tablet, film coated, extended release for oral use. It is used for the management of moderate to severe pain in adults, including postoperative pain and chronic pain management. GNH India supplies Tramadol Hydrochloride 200 mg/1 as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide.

GNH India is committed to providing high-quality pharmaceuticals to meet the needs of healthcare providers and patients globally.

Strength

200 mg/1

Pack Size

100 TABLET, FILM COATED, EXTENDED RELEASE in 1 BOTTLE (33342-270-11)

Manufacturer / TM Owner

Macleods Pharmaceuticals Limited

1
Pack/s
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Indications & Clinical Uses

Tramadol Hydrochloride 200 mg/1 is an opioid analgesic used to manage moderate to severe pain. It is indicated for various conditions, including:

  • Moderate to severe acute pain: Provides relief for short-term pain episodes lasting less than a week.
  • Post-operative pain: Manages pain following surgery.
  • Chronic pain management: Used for long-term pain management when other treatments are inadequate.

How It Works

  • Tramadol Hydrochloride works by binding to μ-opioid receptors in the central nervous system, which helps to reduce the perception of pain. Additionally, it inhibits the reuptake of norepinephrine and serotonin, enhancing its analgesic effects. This dual mechanism contributes to its effectiveness in managing moderate to severe pain.

Side Effects

Tramadol Hydrochloride, like other opioids, can cause a range of side effects. Common Side Effects:

  • Nausea: Feeling sick to your stomach.
  • Dizziness: A sensation of lightheadedness or unsteadiness.
  • Constipation: Difficulty passing stools.
  • Headache: Pain in the head.
  • Somnolence: Feeling sleepy or drowsy.
  • Dry mouth: A lack of moisture in the mouth.

Serious or Rare Side Effects

  • Respiratory depression: Severe breathing difficulties.
  • Severe hypotension: Dangerously low blood pressure.
  • Syncope: Fainting or losing consciousness.
  • Seizures: Uncontrolled electrical disturbances in the brain.
  • Adrenal insufficiency: Inadequate production of adrenal hormones.
  • Serious skin reactions: Severe allergic reactions affecting the skin.

Precautions & Warnings

Tramadol Hydrochloride should be used with caution and under medical supervision. Important precautions include:

  • Avoid in patients with severe respiratory depression: Can exacerbate breathing problems.
  • Monitor for signs of addiction: Regular use can lead to dependence.
  • Use cautiously in patients with a history of seizures: May lower the seizure threshold.
  • Avoid in patients with severe hepatic or renal impairment: May affect drug metabolism and excretion.
  • Store below 25°C: Keep in the original pack, protect from moisture.

Avoid Interactions

Tramadol Hydrochloride can interact with other medications, potentially affecting its efficacy or increasing the risk of side effects. Major Interactions (Avoid):

  • MAO inhibitors: Can cause serious interactions leading to severe side effects.
  • Serotonergic drugs: May increase the risk of serotonin syndrome.
  • CYP3A4 inhibitors: Can increase tramadol levels, leading to toxicity.

Moderate Interactions (Monitor Closely)

  • CNS depressants: May enhance sedative effects.
  • Antidepressants: May increase the risk of serotonin syndrome.
  • Antipsychotics: May enhance sedative effects and increase the risk of side effects.

Frequently Asked Questions

Tramadol Hydrochloride 200 mg/1 is used for the management of moderate to severe pain. It is indicated for conditions such as acute pain, post-operative pain, and chronic pain management when other treatments are inadequate.

Tramadol Hydrochloride works by binding to μ-opioid receptors in the central nervous system, which helps to reduce the perception of pain. Additionally, it inhibits the reuptake of norepinephrine and serotonin, enhancing its analgesic effects.

The dosage of Tramadol Hydrochloride 200 mg/1 is determined by a healthcare provider based on the patient's condition, severity of pain, and response to treatment. It is important to follow the prescribed dosage and not to exceed the recommended dose.

Tramadol Hydrochloride is classified as a Category C drug during pregnancy, meaning it should be used with caution. It is not recommended for use during breastfeeding due to the potential risk of adverse effects on the infant. Always consult a healthcare provider before using this medication during pregnancy or breastfeeding.

To order Tramadol Hydrochloride 200 mg/1 from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets and will ask the buyer to confirm trade or institutional credentials. The team will reply with pricing, availability, shipping, and the import paperwork.

Tramadol Hydrochloride is an opioid analgesic that is used for moderate to severe pain management. Compared to other opioids, it has a lower risk of respiratory depression and a dual mechanism of action that includes inhibiting the reuptake of norepinephrine and serotonin. However, it still carries the risk of addiction and should be used with caution.

Tramadol Hydrochloride 200 mg/1 should be stored below 25°C, in the original pack, and protected from moisture. Keep it out of reach of children and pets. Do not share this medication with others, as misuse is dangerous and against the law.

Tramadol Hydrochloride 200 mg/1 is administered orally as an extended-release tablet. It should be swallowed whole and not chewed, crushed, dissolved, or split before administration. The extended-release formulation is taken once daily, regardless of food intake.

The most serious risks associated with Tramadol Hydrochloride include respiratory depression, severe hypotension, seizures, adrenal insufficiency, and serious skin reactions. It is important to monitor for these risks and seek medical attention if they occur.

Tramadol Hydrochloride 200 mg/1 should not be used by individuals with severe respiratory depression, acute or severe bronchial asthma, significant respiratory depression, acute or severe bronchial asthma in an unmonitored setting, known or suspected gastrointestinal obstruction, during or within 14 days of MAO inhibitor use, and children under 12 years of age.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

References

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