Up and Up Acetaminophen Pm Extra Strength 500 mg/1 (Acetaminophen, Diphenhydramine HCl TABLET, FILM COATED) 500 mg/1

Up & Up Acetaminophen PM Extra Strength 500 mg provides effective pain relief and helps promote sleep. This combination of acetaminophen and diphenhydramine HCl is designed for temporary relief of minor aches and pains with a sleep aid.

Strength

500 mg/1

Pack Size

1 BOTTLE in 1 CARTON (11673-437-78) / 100 TABLET, FILM COATED in 1 BOTTLE

Manufacturer / TM Owner

Target Corporation

Select Quantity

Pack/s

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

First Name

Last Name

Phone

Delivery Country

Delivery PostCode/Zipcode

Select Your Profile

I have read and agree to the terms & conditions, including the privacy policy, return policy, and usage terms as applicable to this request.

Indications & Clinical Uses

Up & Up Acetaminophen PM Extra Strength 500 mg is commonly used for the temporary relief of minor aches and pains, such as headaches, muscle aches, and arthritis pain. The diphenhydramine HCl component also helps to induce sleep, making it suitable for those who experience discomfort that interferes with rest. This medication is often sought after by individuals looking for a combination of pain relief and sleep aid.

Side Effects

When taken as directed, Up & Up Acetaminophen PM Extra Strength 500 mg may help alleviate minor pain and promote sleep. Some users may experience drowsiness due to the diphenhydramine HCl, which is intended to aid in falling asleep. The effects typically last for several hours, providing temporary relief.

Precautions & Warnings

It is important to handle Up & Up Acetaminophen PM Extra Strength 500 mg with care. This medication should not be taken by individuals who are allergic to acetaminophen or diphenhydramine HCl. It is also advisable to consult with a healthcare provider before use, especially if you have any pre-existing medical conditions or are taking other medications.

Avoid Interactions

Up & Up Acetaminophen PM Extra Strength 500 mg may interact with other medications, including those that cause drowsiness. Alcohol should be avoided while taking this medication, as it can enhance the sedative effects. Always inform your healthcare provider about all medications you are taking to avoid potential interactions.

Frequently Asked Questions

This medication is used for the temporary relief of minor aches and pains, such as headaches and muscle aches, and to help promote sleep.

This medication should be taken orally, typically before bedtime, as directed on the packaging or by a healthcare provider.

Yes, the diphenhydramine HCl component in this medication is known to cause drowsiness, which is intended to aid in falling asleep.

No, it is not recommended to take this medication with alcohol, as it can enhance the sedative effects and increase the risk of side effects.

Individuals who are allergic to acetaminophen or diphenhydramine HCl, as well as those with certain medical conditions, should avoid taking this medication unless advised by a healthcare provider.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated: 29 Jul 2026

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.