Product image of Visudyne 15 mg/1 (Verteporfin for Injection) 15 mg/1 INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION supplied by GNH India

Visudyne 15 mg/1

Active Ingredient:
Verteporfin for Injection
Form:
INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION
Brand:
Visudyne
Origin:
USA

Visudyne 15 mg/1 (Verteporfin for Injection INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION) 15 mg/1

Verteporfin, the active ingredient in Visudyne, is a photosensitizer presented as a 15 mg/1 injection, powder, lyophilized, for solution for intravenous use. It is used to treat conditions such as neovascular (wet) age-related macular degeneration, pathologic myopia, and presumed ocular histoplasmosis.

GNH India supplies Visudyne as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide.

Strength

15 mg/1

Pack Size

1 INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION in 1 CARTON (24208-560-15)

Manufacturer / TM Owner

Bausch & Lomb Incorporated

1
Pack/s
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Indications & Clinical Uses

Visudyne is used to treat conditions involving abnormal blood vessel growth in the eye. It is specifically indicated for the following:

  • Neovascular (wet) age-related macular degeneration: Reduces leakage from abnormal blood vessels in the eye.
  • Pathologic myopia: Treats severe nearsightedness that causes vision loss.
  • Presumed ocular histoplasmosis: Manages vision loss due to fungal infection in the eye.

How It Works

  • After activation by red light (689 nm), verteporfin generates reactive oxygen species that cause selective occlusion of neovascular tissue in the eye. This process helps to block the abnormal blood vessels, reducing leakage and slowing vision loss.

Side Effects

Visudyne may cause various side effects, which can be categorized as follows:

Common Side Effects

  • Back pain (temporary)
  • Chest pain (temporary)
  • Constipation
  • Decrease in pain or touch sensitivity
  • Dry, itchy, or painful eyes
  • Injection site reactions such as pain, redness, swelling, bleeding, discoloration, or rash
  • Light sensitivity
  • Nausea
  • Weakness

Serious or Rare Side Effects

  • Seizures
  • Severe decrease in vision (often sudden)
  • Signs of an allergic reaction (e.g., difficulty breathing; hives; swelling of face, lips, tongue, or throat)
  • Appearance of light flashes or floaters
  • Blurred vision
  • Decrease in sharpness of vision
  • Increased blood pressure

Precautions & Warnings

Visudyne should be used with caution and under the supervision of a healthcare professional. Important precautions include:

  • Avoid use if you have porphyria or are allergic to verteporfin or any of its components.
  • Avoid exposure of skin or eyes to direct sunlight or bright indoor light for 2 to 5 days after treatment.
  • Use the largest arm vein possible, preferably the antecubital, for injection.
  • Monitor for signs of allergic reactions or severe vision loss.
  • Store at room temperature and protect from light.

Avoid Interactions

Visudyne may interact with other medications, which can be categorized as follows:

Major Interactions (Avoid)

  • Photosensitizing agents: May increase the risk of photosensitivity reactions.
  • Other medications that cause photosensitivity: May enhance the photosensitivity effects of verteporfin.

Moderate Interactions (Monitor Closely)

  • Medications that affect liver function: May alter the metabolism of verteporfin.
  • Medications that cause blood vessel constriction: May affect the efficacy of verteporfin.
  • Medications that cause blood vessel dilation: May affect the efficacy of verteporfin.

Frequently Asked Questions

Visudyne is used to treat conditions involving abnormal blood vessel growth in the eye, such as neovascular (wet) age-related macular degeneration, pathologic myopia, and presumed ocular histoplasmosis. It helps to reduce leakage from these abnormal blood vessels, slowing vision loss.

Verteporfin, the active ingredient in Visudyne, is a photosensitizer. After activation by red light (689 nm), it generates reactive oxygen species that cause selective occlusion of neovascular tissue in the eye. This process helps to block the abnormal blood vessels, reducing leakage and slowing vision loss.

The dosage of Visudyne is determined by a healthcare professional based on the patient's condition and response to treatment. It is important to follow the prescribed dosage and administration instructions provided by your doctor.

Visudyne is classified as a pregnancy category C drug, meaning it should be used during pregnancy only if the potential benefits outweigh the risks. It is not known whether Verteporfin is excreted in human milk, so caution should be exercised when administering to nursing mothers. Always consult your healthcare provider for personalized advice.

To order Visudyne from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets and will ask the buyer to confirm trade or institutional credentials. The team will then reply with pricing, availability, shipping, and the import paperwork.

Visudyne is one of the treatments available for wet age-related macular degeneration (AMD). It is particularly effective for the predominantly classic form of choroidal neovascularization (CNV). Other treatments may include anti-VEGF injections, which work by blocking the growth of abnormal blood vessels. The choice of treatment depends on the specific condition and the patient's response.

Visudyne should be stored at room temperature and protected from light. It is important to follow the storage instructions provided with the medication to ensure its effectiveness and safety. Always handle the medication with care and follow the administration guidelines provided by your healthcare professional.

Visudyne is administered by intravenous infusion, usually in the arm, over a 10-minute period. After a few minutes, a laser light is shone on the eye to activate the medication. This procedure is typically performed by a healthcare professional in a clinical setting.

The most serious risks associated with Visudyne include severe decrease in vision, seizures, and signs of an allergic reaction such as difficulty breathing, hives, or swelling of the face, lips, tongue, or throat. If any of these symptoms occur, seek immediate medical attention.

Visudyne should not be used by individuals who have porphyria, are allergic to Verteporfin or any of its components, or have severe liver dysfunction. Always consult your healthcare provider to determine if Visudyne is suitable for you.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

References

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