Product image of Xiaflex (Collagenase Clostridium Histolyticum) 0.9mg/vial Vials supplied by GNH India

Xiaflex

Active Ingredient:
Collagenase Clostridium Histolyticum
Form:
Vials
Brand:
Xiaflex
Origin:
USA

Xiaflex (Collagenase Clostridium Histolyticum Vials) 0.9mg/vial

Xiaflex (Collagenase Clostridium Histolyticum) is a prescription enzyme treatment for Dupuytren’s contracture and Peyronie’s disease. Administered via injection, it targets collagen buildup. Store between 2-8°C to maintain potency. Not for self-administration.

Strength

0.9mg/vial

Pack Size

1s

Storage

2-8°

Manufacturer / TM Owner

Endo Pharmaceuticals

1
Pack/s
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Indications & Clinical Uses

  • Xiaflex is used to treat Dupuytren’s contracture, a condition causing finger contractures due to collagen buildup in the hand. It is also prescribed for Peyronie’s disease, which involves penile curvature from fibrous plaque. This medication helps break down collagen fibers, improving flexibility and function. It is typically used when conservative treatments are ineffective.

Side Effects

  • Xiaflex works by breaking down collagen, the protein responsible for fibrous tissue buildup. After injection, it may reduce contractures or curvature within days to weeks. Swelling, bruising, or pain at the injection site are common temporary effects. Some patients report improved range of motion or reduced deformity over time.

Precautions & Warnings

  • Xiaflex should only be administered by a healthcare professional trained in its use. Avoid injections near blood vessels or nerves to reduce injury risk. Patients with bleeding disorders or those taking blood thinners may need extra monitoring. Report severe pain, swelling, or signs of infection immediately.

Avoid Interactions

  • Xiaflex may interact with blood thinners like warfarin or antiplatelets such as aspirin, increasing bleeding risk. No known interactions with foods or supplements, but alcohol may worsen swelling. Always inform your provider about all medications before treatment. Concomitant use with other collagenase products is not recommended.

Frequently Asked Questions

Xiaflex is used to treat Dupuytren’s contracture and Peyronie’s disease by breaking down collagen buildup.

Xiaflex is given as an injection by a healthcare provider, typically in a clinical setting.

Common side effects include swelling, bruising, or pain at the injection site.

No, Xiaflex requires a prescription and should only be obtained through licensed pharmacies.

Store Xiaflex vials refrigerated between 2-8°C and protect from light.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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